Abstract
Two new trichothecenes were isolated along with T-2 toxin, neosolaniol, and HT-2 toxin from the culture filtrate of Fusarium sporotrichioides strain M-1-1. The structures of the new toxins were characterized to be 4 beta, 8 alpha-diacetoxy-12,13-epoxytrichothec-9-ene-3 alpha, 15-diol (designated NT-1) and 4 beta-acetoxy-12,13-epoxy-trichothec-9-ene-3 alpha,8 alpha,15-triol (designated NT-2).
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Selected References
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- Ishii K., Sakai K., Ueno Y., Tsunoda H., Enomoto M. Solaniol, a toxic metabolite of Fusarium solani. Appl Microbiol. 1971 Oct;22(4):718–720. doi: 10.1128/am.22.4.718-720.1971. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Ueno Y., Hosoya M., Ishikawa Y. Inhibitory effects of mycotoxins on the protein synthesis in rabbit reticulocytes. J Biochem. 1969 Sep;66(3):419–422. doi: 10.1093/oxfordjournals.jbchem.a129163. [DOI] [PubMed] [Google Scholar]
- Ueno Y., Ishii K., Sakai K., Kanaeda S., Tsunoda H. Toxicological approaches to the metabolites of Fusaria. IV. Microbial survey on "bean-hulls poisoning of horses" with the isolation of toxic trichothecenes, neosolaniol and T-2 toxin of Fusarium solani M-1-1. Jpn J Exp Med. 1972 Jun;42(3):187–203. [PubMed] [Google Scholar]
- Ueno Y., Ishikawa Y., Saito-Amakai K., Tsunoda H. Environmental factors influencing the production of fusarenon-X, a cytotoxic mycotoxin of Fusarium nivale Fn 2B. Chem Pharm Bull (Tokyo) 1970 Feb;18(2):304–312. doi: 10.1248/cpb.18.304. [DOI] [PubMed] [Google Scholar]
- Ueno Y., Nakajima M., Sakai K., Ishii K., Sato N. Comparative toxicology of trichothec mycotoxins: inhibition of protein synthesis in animal cells. J Biochem. 1973 Aug;74(2):285–296. [PubMed] [Google Scholar]
