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Expression of CD22 as assessed by monoclonal antibody (mAb) 2D6 is affected by expression of FcγRIIb. Binding of the anti-CD22 mAb 2D6 to B220+ splenocytes (i and iii), or B-cell lines (ii), was examined by flow cytometry. Histograms are representative of at least four independent experiments in each case.
