Skip to main content
Applied and Environmental Microbiology logoLink to Applied and Environmental Microbiology
. 1981 Dec;42(6):1130–1131. doi: 10.1128/aem.42.6.1130-1131.1981

Mutants of Corynebacterium diphtheriae PW8 that produce toxin in medium with excess iron.

C Ishii-Kanei, T Uchida, M Yoneda
PMCID: PMC244166  PMID: 6797351

Abstract

Two mutants that produce toxin in medium with excess iron were isolated from the PW8 strain of Corynebacterium diphtheriae. These mutants produced as much toxin in medium containing excess iron (3 mug of Fe2+ per ml) as did the parent PW8 strain in iron-depleted medium, and they will be very useful for easy production of toxin.

Full text

PDF
1130

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Gill D. M., Pappenheimer A. M., Jr Structure-activity relationships in diphtheria toxin. J Biol Chem. 1971 Mar 10;246(5):1492–1495. [PubMed] [Google Scholar]
  2. Ishii-Kanei C., Uchida T., Yoneda M. Isolation of a cured strain from Corynebacterium diphtheriae PW8. Infect Immun. 1979 Sep;25(3):1081–1083. doi: 10.1128/iai.25.3.1081-1083.1979. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Kanei C., Uchida T., Yoneda M. Isolation from corynebacterium diphtheriae C7(beta) of bacterial mutants that produce toxin in medium with excess iron. Infect Immun. 1977 Oct;18(1):203–209. doi: 10.1128/iai.18.1.203-209.1977. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Weber K., Osborn M. The reliability of molecular weight determinations by dodecyl sulfate-polyacrylamide gel electrophoresis. J Biol Chem. 1969 Aug 25;244(16):4406–4412. [PubMed] [Google Scholar]
  5. YONEDA M. A new culture method designed for kinetic studies on diphtheria toxin production. Br J Exp Pathol. 1957 Apr;38(2):190–193. [PMC free article] [PubMed] [Google Scholar]

Articles from Applied and Environmental Microbiology are provided here courtesy of American Society for Microbiology (ASM)

RESOURCES