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. 1996;9(3):145–148. doi: 10.1155/1996/64373

Prospective Randomized Trial Comparing Endoscopic Sphincterotomy Followed by Surgery with Surgery Alone in Good Risk Patients with Choledocholithiasis

R Kapoor 1, S P Kaushik 1, V A Saraswat 2, G Choudhuri 2, S S Sikora 1, R Saxena 1, V K Kapoor 1
PMCID: PMC2443081  PMID: 8725454

Abstract

Background: Role of endoscopic sphincterotomy (ES) in high risk patients with choledocholithiasis is established but its role in good risk patients is unclear.

Design: A prospective randomized trial of endoscopic sphincterotomy followed by surgery (ES + S) versus surgery alone (SA) in good risk patients with choledocholithiasis.

Setting: A tertiary level referral hospital in north India; July 1991 to October 1993.

Patients and methods: Thirty three out of 60 patients with choledocholithiasis were found suitable for randomization-16 were randomised to ES+S group and 17 to SA group.

Results: Common bile duct clearance was achieved in 11/13 (85%) patients in ES+S group and in 13/15 (87%) in SA group. Major complications occurred in 4/13 (31%) patients in ES+S group and 3/16 (19%) patients in SA group. These differences were not statistically significant, but patients in ES+S group were exposed to morbidity twice, procedure related morbidity of ES being 23%. No significant differences were observed in hospital stay and cost of treatment.

Conclusions: Results of this trial do not support use of precholecystectomy ES in good risk patients with choledocholithiasis, since it did not offer any advantage over surgery alone.

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