Abstract
Since our last issue, several important genomes have been completely or ‘almost completely’ sequenced. The debate over the number of human genes has flared up once more, with one computational and one experimental study into the annotation of the human genome. The mouse genome project has a clone fingerprint map to aid their sequencing effort. The SAGE technique has been applied to Drosophila and the US National Science Foundation announced increased spending on plant genome research.
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Selected References
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- Camargo A. A., Samaia H. P., Dias-Neto E., Simão D. F., Migotto I. A., Briones M. R., Costa F. F., Nagai M. A., Verjovski-Almeida S., Zago M. A. The contribution of 700,000 ORF sequence tags to the definition of the human transcriptome. Proc Natl Acad Sci U S A. 2001 Oct 9;98(21):12103–12108. doi: 10.1073/pnas.201182798. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Das M., Burge C. B., Park E., Colinas J., Pelletier J. Assessment of the total number of human transcription units. Genomics. 2001 Sep;77(1-2):71–78. doi: 10.1006/geno.2001.6620. [DOI] [PubMed] [Google Scholar]
- Dunham I., Shimizu N., Roe B. A., Chissoe S., Hunt A. R., Collins J. E., Bruskiewich R., Beare D. M., Clamp M., Smink L. J. The DNA sequence of human chromosome 22. Nature. 1999 Dec 2;402(6761):489–495. doi: 10.1038/990031. [DOI] [PubMed] [Google Scholar]
- Jasper H., Benes V., Schwager C., Sauer S., Clauder-Münster S., Ansorge W., Bohmann D. The genomic response of the Drosophila embryo to JNK signaling. Dev Cell. 2001 Oct;1(4):579–586. doi: 10.1016/s1534-5807(01)00045-4. [DOI] [PubMed] [Google Scholar]
- Kawarabayasi Y., Hino Y., Horikawa H., Jin-no K., Takahashi M., Sekine M., Baba S., Ankai A., Kosugi H., Hosoyama A. Complete genome sequence of an aerobic thermoacidophilic crenarchaeon, Sulfolobus tokodaii strain7. DNA Res. 2001 Aug 31;8(4):123–140. doi: 10.1093/dnares/8.4.123. [DOI] [PubMed] [Google Scholar]
- McClelland M., Sanderson K. E., Spieth J., Clifton S. W., Latreille P., Courtney L., Porwollik S., Ali J., Dante M., Du F. Complete genome sequence of Salmonella enterica serovar Typhimurium LT2. Nature. 2001 Oct 25;413(6858):852–856. doi: 10.1038/35101614. [DOI] [PubMed] [Google Scholar]
- Parkhill J., Dougan G., James K. D., Thomson N. R., Pickard D., Wain J., Churcher C., Mungall K. L., Bentley S. D., Holden M. T. Complete genome sequence of a multiple drug resistant Salmonella enterica serovar Typhi CT18. Nature. 2001 Oct 25;413(6858):848–852. doi: 10.1038/35101607. [DOI] [PubMed] [Google Scholar]
- Parkhill J., Wren B. W., Thomson N. R., Titball R. W., Holden M. T., Prentice M. B., Sebaihia M., James K. D., Churcher C., Mungall K. L. Genome sequence of Yersinia pestis, the causative agent of plague. Nature. 2001 Oct 4;413(6855):523–527. doi: 10.1038/35097083. [DOI] [PubMed] [Google Scholar]