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. 2003 Jul;4(4):406–409. doi: 10.1002/cfg.308

The Prediction of Membrane Protein Structure and Genome Structural Annotation

Pier Luigi Martelli 1, Piero Fariselli 1, Gianluca Tasco 1, Rita Casadio 1,✉
PMCID: PMC2447372  PMID: 18629086

Abstract

New methods, essentially based on hidden Markov models (HMM) and neural networks (NN), can predict the topography of both β-barrel and all-α membrane proteins with high accuracy and a low rate of false positives and false negatives. These methods have been integrated in a suite of programs to filter proteomes of Gram-negative bacteria, searching for new membrane proteins.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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