Abstract
The Malthus Microbiological Growth Analyser has proved to be sensitive in detecting conductivity changes due to anaerobic metabolism in a number of widely used blood culture media. Freshly prepared cooked meat media and Thiol medium yielded the greatest gross conductivity changes, and were more sensitive of anaerobic metabolism than other media. Failure of the instrument to detect anaerobic metabolism was a problem particularly associated with growth in the thioglycollate medium. False positive detections of growth were attributed to a number of factors including electrode instability (6.0%) and bacterial contamination (8.75%).
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Selected References
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- Barr J. G. A cooked meat blood culture medium; shelf-life and clinical evaluation compared with other systems. J Infect. 1980 Sep;2(3):247–258. doi: 10.1016/s0163-4453(80)90698-2. [DOI] [PubMed] [Google Scholar]
- Baynes N. C., Comrie J., Prain J. H. Detection of bacterial growth by the Malthus conductance meter. Med Lab Sci. 1983 Apr;40(2):149–158. [PubMed] [Google Scholar]
- Brown D. F., Warner M., Taylor C. E., Warren R. E. Automated detection of micro-organisms in blood cultures by means of the Malthus Microbiological Growth Analyser. J Clin Pathol. 1984 Jan;37(1):65–69. doi: 10.1136/jcp.37.1.65. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Dorn G. L., Burson G. G., Haynes J. R. Blood culture technique based on centrifugation: clinical evaluation. J Clin Microbiol. 1976 Mar;3(3):258–263. doi: 10.1128/jcm.3.3.258-263.1976. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Ripa K. T., Mårdh P. A., Hovelius B., Ljungholm K. Microcalorimetry as a tool for evaluation of blood culture media. J Clin Microbiol. 1977 Apr;5(4):393–396. doi: 10.1128/jcm.5.4.393-396.1977. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Shanson D. C., Barnicoat An experimental comparison of Thiol broth with Brewer's thioglycollate for anaerobic blood cultures. J Clin Pathol. 1975 May;28(5):407–409. doi: 10.1136/jcp.28.5.407. [DOI] [PMC free article] [PubMed] [Google Scholar]
