Abstract
Potential relationships between the development of nickel allergy and previous ear piercing or orthodontic treatment with nickel-containing appliances were studied in 294 patients. We found 77 (31.2%) of 247 patients with pierced ears were allergic to nickel compared to only three (6.4%) patients without pierced ears (p = 0.001), which confirms earlier suggestions that nickel allergy (as assessed by patch testing) is promoted by ear piercing. If orthodontic treatment preceded the event of ear piercing, the frequency of nickel allergy was reduced from 36% to 25%. This supports the view that oral allergenic contacts may induce immunological tolerance.
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- Boss A., Menné T. Nickel sensitization from ear piercing. Contact Dermatitis. 1982 May;8(3):211–213. doi: 10.1111/j.1600-0536.1982.tb04191.x. [DOI] [PubMed] [Google Scholar]
- Edman B., Möller H. Trends and forecasts for standard allergens in a 12-year patch test material. Contact Dermatitis. 1982 Mar;8(2):95–104. doi: 10.1111/j.1600-0536.1982.tb04153.x. [DOI] [PubMed] [Google Scholar]
- Lammintausta K., Kalimo K., Havu V. K. Occurrence of contact allergy and hand eczemas in hospital wet work. Contact Dermatitis. 1982 Mar;8(2):84–90. doi: 10.1111/j.1600-0536.1982.tb04151.x. [DOI] [PubMed] [Google Scholar]
- Larsson-Stymne B., Widström L. Ear piercing--a cause of nickel allergy in schoolgirls? Contact Dermatitis. 1985 Nov;13(5):289–293. doi: 10.1111/j.1600-0536.1985.tb02580.x. [DOI] [PubMed] [Google Scholar]
- Lindemayr H. Das Friseurekzem. Derm Beruf Umwelt. 1984;32(1):5–13. [PubMed] [Google Scholar]
- Menne T. The prevalence of nickel allergy among women. An epidemiological study in hospitalized female patients. Derm Beruf Umwelt. 1978;26(4):123–125. [PubMed] [Google Scholar]
- Menné T., Borgan O., Green A. Nickel allergy and hand dermatitis in a stratified sample of the Danish female population: an epidemiological study including a statistic appendix. Acta Derm Venereol. 1982;62(1):35–41. [PubMed] [Google Scholar]
- Menné T., Brandup F., Thestrup-Pedersen K., Veien N. K., Andersen J. R., Yding F., Valeur G. Patch test reactivity to nickel alloys. Contact Dermatitis. 1987 May;16(5):255–259. doi: 10.1111/j.1600-0536.1987.tb01448.x. [DOI] [PubMed] [Google Scholar]
- Peltonen L. Nickel sensitivity in the general population. Contact Dermatitis. 1979 Jan;5(1):27–32. doi: 10.1111/j.1600-0536.1979.tb05531.x. [DOI] [PubMed] [Google Scholar]
- Prystowsky S. D., Allen A. M., Smith R. W., Nonomura J. H., Odom R. B., Akers W. A. Allergic contact hypersensitivity to nickel, neomycin, ethylenediamine, and benzocaine. Relationships between age, sex, history of exposure, and reactivity to standard patch tests and use tests in a general population. Arch Dermatol. 1979 Aug;115(8):959–962. doi: 10.1001/archderm.115.8.959. [DOI] [PubMed] [Google Scholar]
- Rystedt I., Fischer T. Relationship between nickel and cobalt sensitization in hard metal workers. Contact Dermatitis. 1983 May;9(3):195–200. doi: 10.1111/j.1600-0536.1983.tb04357.x. [DOI] [PubMed] [Google Scholar]
- Tomasi T. B., Jr Oral tolerance. Transplantation. 1980 May;29(5):353–356. doi: 10.1097/00007890-198005000-00001. [DOI] [PubMed] [Google Scholar]
- Vreeburg K. J., de Groot K., von Blomberg M., Scheper R. J. Induction of immunological tolerance by oral administration of nickel and chromium. J Dent Res. 1984 Feb;63(2):124–128. doi: 10.1177/00220345840630020501. [DOI] [PubMed] [Google Scholar]
- van der Burg C. K., Bruynzeel D. P., Vreeburg K. J., von Blomberg B. M., Scheper R. J. Hand eczema in hairdressers and nurses: a prospective study. I. Evaluation of atopy and nickel hypersensitivity at the start of apprenticeship. Contact Dermatitis. 1986 May;14(5):275–279. doi: 10.1111/j.1600-0536.1986.tb05275.x. [DOI] [PubMed] [Google Scholar]