Abstract
Fetal hydrops (hydrops fetalis) remains a significant cause of fetal and neonatal mortality. The decreased incidence of rhesus iso-immunisation due to prophylaxis with rhesus immune globulin (anti-D), improved antenatal ultrasound screening, and advances in neonatal intensive care have greatly altered the clinical outlook in this condition. A retrospective review of all 27 liveborn cases of hydrops in the Royal Maternity Hospital, Belfast in the period 1974-89 showed that in the last five years 40% of cases were non-immune in origin. The mortality rate fell from 100% in the first part of the study to 50% in the second.
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Selected References
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- Bang J., Bock J. E., Trolle D. Ultrasound-guided fetal intravenous transfusion for severe rhesus haemolytic disease. Br Med J (Clin Res Ed) 1982 Feb 6;284(6313):373–374. doi: 10.1136/bmj.284.6313.373. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Harman C. R., Manning F. A., Bowman J. M., Lange I. R. Severe Rh disease--poor outcome is not inevitable. Am J Obstet Gynecol. 1983 Apr 1;145(7):823–829. doi: 10.1016/0002-9378(83)90686-5. [DOI] [PubMed] [Google Scholar]
- Holzgreve W., Curry C. J., Golbus M. S., Callen P. W., Filly R. A., Smith J. C. Investigation of nonimmune hydrops fetalis. Am J Obstet Gynecol. 1984 Dec 1;150(7):805–812. doi: 10.1016/0002-9378(84)90453-8. [DOI] [PubMed] [Google Scholar]
- Hutchison A. A., Drew J. H., Yu V. Y., Williams M. L., Fortune D. W., Beischer N. A. Nonimmunologic hydrops fetalis: a review of 61 cases. Obstet Gynecol. 1982 Mar;59(3):347–352. [PubMed] [Google Scholar]
- Macafee C. A., Fortune D. W., Beischer N. A. Non-immunological hydrops fetalis. J Obstet Gynaecol Br Commonw. 1970 Mar;77(3):226–237. doi: 10.1111/j.1471-0528.1970.tb03511.x. [DOI] [PubMed] [Google Scholar]
- Machin G. A. Hydrops revisited: literature review of 1,414 cases published in the 1980s. Am J Med Genet. 1989 Nov;34(3):366–390. doi: 10.1002/ajmg.1320340313. [DOI] [PubMed] [Google Scholar]
- O'Sullivan J. F. Rhesus and other antibodies. Clin Obstet Gynaecol. 1982 Apr;9(1):91–99. [PubMed] [Google Scholar]