Skip to main content
PMC home page
Yeast (Chichester, England) logoLink to Yeast (Chichester, England)

Danio Rerio, the Zebrafish

Jo Wixon 1,✉
PMCID: PMC2448373  PMID: 11025533

Abstract

The zebrafish has long been a favourite model for the study of vertebrate development. Here we provide an overview of the current state of knowledge and resources for the study of this fish, with comments on the future direction of zebrafish genomics from Professor Mark Fishman and Dr Stephen Wilson.

Full Text

The Full Text of this article is available as a PDF (100.7 KB).

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Amemiya C. T., Zon L. I. Generation of a zebrafish P1 artificial chromosome library. Genomics. 1999 Jun 1;58(2):211–213. doi: 10.1006/geno.1999.5827. [DOI] [PubMed] [Google Scholar]
  2. Amores A., Force A., Yan Y. L., Joly L., Amemiya C., Fritz A., Ho R. K., Langeland J., Prince V., Wang Y. L. Zebrafish hox clusters and vertebrate genome evolution. Science. 1998 Nov 27;282(5394):1711–1714. doi: 10.1126/science.282.5394.1711. [DOI] [PubMed] [Google Scholar]
  3. Drummond I. A. The zebrafish pronephros: a genetic system for studies of kidney development. Pediatr Nephrol. 2000 May;14(5):428–435. doi: 10.1007/s004670050788. [DOI] [PubMed] [Google Scholar]
  4. Hukriede N. A., Joly L., Tsang M., Miles J., Tellis P., Epstein J. A., Barbazuk W. B., Li F. N., Paw B., Postlethwait J. H. Radiation hybrid mapping of the zebrafish genome. Proc Natl Acad Sci U S A. 1999 Aug 17;96(17):9745–9750. doi: 10.1073/pnas.96.17.9745. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Hyatt T. M., Ekker S. C. Vectors and techniques for ectopic gene expression in zebrafish. Methods Cell Biol. 1999;59:117–126. doi: 10.1016/s0091-679x(08)61823-3. [DOI] [PubMed] [Google Scholar]
  6. Johnson S. L., Gates M. A., Johnson M., Talbot W. S., Horne S., Baik K., Rude S., Wong J. R., Postlethwait J. H. Centromere-linkage analysis and consolidation of the zebrafish genetic map. Genetics. 1996 Apr;142(4):1277–1288. doi: 10.1093/genetics/142.4.1277. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Kelly P. D., Chu F., Woods I. G., Ngo-Hazelett P., Cardozo T., Huang H., Kimm F., Liao L., Yan Y. L., Zhou Y. Genetic linkage mapping of zebrafish genes and ESTs. Genome Res. 2000 Apr;10(4):558–567. doi: 10.1101/gr.10.4.558. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Krauss S., Concordet J. P., Ingham P. W. A functionally conserved homolog of the Drosophila segment polarity gene hh is expressed in tissues with polarizing activity in zebrafish embryos. Cell. 1993 Dec 31;75(7):1431–1444. doi: 10.1016/0092-8674(93)90628-4. [DOI] [PubMed] [Google Scholar]
  9. Kwok C., Korn R. M., Davis M. E., Burt D. W., Critcher R., McCarthy L., Paw B. H., Zon L. I., Goodfellow P. N., Schmitt K. Characterization of whole genome radiation hybrid mapping resources for non-mammalian vertebrates. Nucleic Acids Res. 1998 Aug 1;26(15):3562–3566. doi: 10.1093/nar/26.15.3562. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Lacroix L., Arimondo P. B., Takasugi M., Hélène C., Mergny J. L. Pyrimidine morpholino oligonucleotides form a stable triple helix in the absence of magnesium ions. Biochem Biophys Res Commun. 2000 Apr 13;270(2):363–369. doi: 10.1006/bbrc.2000.2438. [DOI] [PubMed] [Google Scholar]
  11. Li Y. X., Farrell M. J., Liu R., Mohanty N., Kirby M. L. Double-stranded RNA injection produces null phenotypes in zebrafish. Dev Biol. 2000 Jan 15;217(2):394–405. doi: 10.1006/dbio.1999.9540. [DOI] [PubMed] [Google Scholar]
  12. Linney E., Hardison N. L., Lonze B. E., Lyons S., DiNapoli L. Transgene expression in zebrafish: A comparison of retroviral-vector and DNA-injection approaches. Dev Biol. 1999 Sep 1;213(1):207–216. doi: 10.1006/dbio.1999.9376. [DOI] [PubMed] [Google Scholar]
  13. Malicki J., Neuhauss S. C., Schier A. F., Solnica-Krezel L., Stemple D. L., Stainier D. Y., Abdelilah S., Zwartkruis F., Rangini Z., Driever W. Mutations affecting development of the zebrafish retina. Development. 1996 Dec;123:263–273. doi: 10.1242/dev.123.1.263. [DOI] [PubMed] [Google Scholar]
  14. Postlethwait J. H., Yan Y. L., Gates M. A., Horne S., Amores A., Brownlie A., Donovan A., Egan E. S., Force A., Gong Z. Vertebrate genome evolution and the zebrafish gene map. Nat Genet. 1998 Apr;18(4):345–349. doi: 10.1038/ng0498-345. [DOI] [PubMed] [Google Scholar]
  15. Saszik S., Bilotta J., Givin C. M. ERG assessment of zebrafish retinal development. Vis Neurosci. 1999 Sep-Oct;16(5):881–888. doi: 10.1017/s0952523899165076. [DOI] [PubMed] [Google Scholar]
  16. Scheer N., Campos-Ortega J. A. Use of the Gal4-UAS technique for targeted gene expression in the zebrafish. Mech Dev. 1999 Feb;80(2):153–158. doi: 10.1016/s0925-4773(98)00209-3. [DOI] [PubMed] [Google Scholar]
  17. Shimoda N., Knapik E. W., Ziniti J., Sim C., Yamada E., Kaplan S., Jackson D., de Sauvage F., Jacob H., Fishman M. C. Zebrafish genetic map with 2000 microsatellite markers. Genomics. 1999 Jun 15;58(3):219–232. doi: 10.1006/geno.1999.5824. [DOI] [PubMed] [Google Scholar]
  18. Stainier D. Y., Fouquet B., Chen J. N., Warren K. S., Weinstein B. M., Meiler S. E., Mohideen M. A., Neuhauss S. C., Solnica-Krezel L., Schier A. F. Mutations affecting the formation and function of the cardiovascular system in the zebrafish embryo. Development. 1996 Dec;123:285–292. doi: 10.1242/dev.123.1.285. [DOI] [PubMed] [Google Scholar]
  19. Wargelius A., Ellingsen S., Fjose A. Double-stranded RNA induces specific developmental defects in zebrafish embryos. Biochem Biophys Res Commun. 1999 Sep 16;263(1):156–161. doi: 10.1006/bbrc.1999.1343. [DOI] [PubMed] [Google Scholar]
  20. Yan Y. L., Talbot W. S., Egan E. S., Postlethwait J. H. Mutant rescue by BAC clone injection in zebrafish. Genomics. 1998 Jun 1;50(2):287–289. doi: 10.1006/geno.1998.5304. [DOI] [PubMed] [Google Scholar]

Articles from Yeast (Chichester, England) are provided here courtesy of Wiley

RESOURCES