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The Ulster Medical Journal logoLink to The Ulster Medical Journal
. 1993 Apr;62(1):50–57.

Antibiotic pharmacoeconomics: an attempt to find the real cost of hospital antibiotic prescribing.

J R Kerr 1, J G Barr 1, E T Smyth 1, J O'Hare 1, P M Bell 1, M E Callender 1
PMCID: PMC2449013  PMID: 8516976

Abstract

Antibiotics account for a large part of all hospital pharmacy budgets, but the actual cost of their prescription is unknown. These costs include intravenous administration, labour, serum antibiotic assay, monitoring of haematological and biochemical indices, disposal of sharps and adverse effects. An in-house method of costing antibiotic therapy is presented, to quantify these hidden expenses. Since not only an awareness, but an accurate quantification, of hidden costs is required, a study of various hospital procedures relating directly to antibiotic therapy was undertaken in an acute medical ward; this involved the identification of particular staff members performing various procedures, consumables used and time taken. The cost of five-day courses of gentamicin, penicillin G, ampicillin, flucloxacillin, cefuroxime, ceftotaxime and erythromycin has been calculated; drug and hidden costs for each are presented graphically for comparison. The breakdown cost for gentamicin is presented to illustrate the method. The costing of adverse effects has not been attempted. We suggest that costings of this sort are used in cost-benefit analysis of antibiotic use. These calculations have been incorporated into a computer spreadsheet and this costing service will be offered to clinical areas of our hospital.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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