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. 1991 Apr;35(4):760–763. doi: 10.1128/aac.35.4.760

Activities of various macrolide antibiotics against Mycobacterium leprae infection in mice.

R H Gelber 1, P Siu 1, M Tsang 1, L P Murray 1
PMCID: PMC245094  PMID: 1648889

Abstract

We evaluated the activities of several macrolide antibiotics against M. leprae infections in mouse footpads. Erythromycin and azithromycin were inactive, while both roxithromycin and clarithromycin were found to be consistently active and, in fact, bactericidal. By both methods, clarithromycin was found to be superior to roxithromycin, a finding which, at least in part, may be a consequence of the higher levels of clarithromycin at the site of infection.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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