Skip to main content
PMC home page
Antimicrobial Agents and Chemotherapy logoLink to Antimicrobial Agents and Chemotherapy
. 1991 May;35(5):791–795. doi: 10.1128/aac.35.5.791

Plasmid-encoded fosfomycin resistance.

J E Suárez 1, M C Mendoza 1
PMCID: PMC245108  PMID: 1854159

Full text

PDF
791

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Arca P., García P., Hardisson C., Suárez J. E. Purification and study of a bacterial glutathione S-transferase. FEBS Lett. 1990 Apr 9;263(1):77–79. doi: 10.1016/0014-5793(90)80709-r. [DOI] [PubMed] [Google Scholar]
  2. Arca P., Hardisson C., Suárez J. E. Purification of a glutathione S-transferase that mediates fosfomycin resistance in bacteria. Antimicrob Agents Chemother. 1990 May;34(5):844–848. doi: 10.1128/aac.34.5.844. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Arca P., Rico M., Braña A. F., Villar C. J., Hardisson C., Suárez J. E. Formation of an adduct between fosfomycin and glutathione: a new mechanism of antibiotic resistance in bacteria. Antimicrob Agents Chemother. 1988 Oct;32(10):1552–1556. doi: 10.1128/aac.32.10.1552. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Barbieri C., Caldara R., Testori G., Piepoli V., Trezzi R., Romussi M., Ferrari C. Oral glucose tolerance and insulin response after one week's clonidine treatment in hypertensive patients. Acta Diabetol Lat. 1981;18(1):59–63. doi: 10.1007/BF02056107. [DOI] [PubMed] [Google Scholar]
  5. Benveniste R., Davies J. Aminoglycoside antibiotic-inactivating enzymes in actinomycetes similar to those present in clinical isolates of antibiotic-resistant bacteria. Proc Natl Acad Sci U S A. 1973 Aug;70(8):2276–2280. doi: 10.1073/pnas.70.8.2276. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Bibb M. J., Findlay P. R., Johnson M. W. The relationship between base composition and codon usage in bacterial genes and its use for the simple and reliable identification of protein-coding sequences. Gene. 1984 Oct;30(1-3):157–166. doi: 10.1016/0378-1119(84)90116-1. [DOI] [PubMed] [Google Scholar]
  7. Borsa F., Leroy A., Fillastre J. P., Godin M., Moulin B. Comparative pharmacokinetics of tromethamine fosfomycin and calcium fosfomycin in young and elderly adults. Antimicrob Agents Chemother. 1988 Jun;32(6):938–941. doi: 10.1128/aac.32.6.938. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Cadórniga R., Diaz Fierros M., Olay T. Pharmacokinetic study of fosfomycin and its bioavailability. Chemotherapy. 1977;23 (Suppl 1):159–174. doi: 10.1159/000222043. [DOI] [PubMed] [Google Scholar]
  9. Cassidy P. J., Kahan F. M. A stable enzyme-phosphoenolpyruvate intermediate in the synthesis of uridine-5'-diphospho-N-acetyl-2-amino-2-deoxyglucose 3-O-enolpyruvyl ether. Biochemistry. 1973 Mar 27;12(7):1364–1374. doi: 10.1021/bi00731a017. [DOI] [PubMed] [Google Scholar]
  10. Christensen B. G., Leanza W. J., Beattie T. R., Patchett A. A., Arison B. H., Ormond R. E., Kuehl F. A., Jr, Albers-Schonberg G., Jardetzky O. Phosphonomycin: structure and synthesis. Science. 1969 Oct 3;166(3901):123–125. doi: 10.1126/science.166.3901.123. [DOI] [PubMed] [Google Scholar]
  11. Di Ilio C., Aceto A., Piccolomini R., Allocati N., Faraone A., Cellini L., Ravagnan G., Federici G. Purification and characterization of three forms of glutathione transferase from Proteus mirabilis. Biochem J. 1988 Nov 1;255(3):971–975. doi: 10.1042/bj2550971. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Etienne J., Gerbaud G., Courvalin P., Fleurette J. Plasmid-mediated resistance to fosfomycin in Staphylococcus epidermidis. FEMS Microbiol Lett. 1989 Oct 1;52(1-2):133–137. doi: 10.1016/0378-1097(89)90184-5. [DOI] [PubMed] [Google Scholar]
  13. Faragó E., Kiss I. J., Nábrádi Z. Serum and lung tissue levels of fosfomycin in humans. Int J Clin Pharmacol Ther Toxicol. 1980 Dec;18(12):554–558. [PubMed] [Google Scholar]
  14. Figueredo V. M., Neu H. C. Synergy of ciprofloxacin with fosfomycin in vitro against Pseudomonas isolates from patients with cystic fibrosis. J Antimicrob Chemother. 1988 Jul;22(1):41–50. doi: 10.1093/jac/22.1.41. [DOI] [PubMed] [Google Scholar]
  15. Forsgren A., Walder M. Antimicrobial activity of fosfomycin in vitro. J Antimicrob Chemother. 1983 May;11(5):467–471. doi: 10.1093/jac/11.5.467. [DOI] [PubMed] [Google Scholar]
  16. Fujita K. An effect of fosfomycin on the pharmacokinetics of amikacin. J Antibiot (Tokyo) 1984 Apr;37(4):408–412. doi: 10.7164/antibiotics.37.408. [DOI] [PubMed] [Google Scholar]
  17. García-Lobo J. M., León J., Navas J., Ortiz J. M. Cloning and expression in minicells of the determinant of resistance to fosfomycin from the transposon Tn2921. Plasmid. 1984 May;11(3):243–247. doi: 10.1016/0147-619x(84)90030-1. [DOI] [PubMed] [Google Scholar]
  18. García-Lobo J. M., Ortiz J. M. Tn292l, a transposon encoding fosfomycin resistance. J Bacteriol. 1982 Jul;151(1):477–479. doi: 10.1128/jb.151.1.477-479.1982. [DOI] [PMC free article] [PubMed] [Google Scholar]
  19. Gatermann S., Schulz E., Marre R. The microbiological efficacy of the combination of fosfomycin and vancomycin against clinically relevant staphylococci. Infection. 1989 Jan-Feb;17(1):35–37. doi: 10.1007/BF01643498. [DOI] [PubMed] [Google Scholar]
  20. Greenwood D., Jones A., Eley A. Factors influencing the activity of the trometamol salt of fosfomycin. Eur J Clin Microbiol. 1986 Feb;5(1):29–34. doi: 10.1007/BF02013457. [DOI] [PubMed] [Google Scholar]
  21. Hardisson C., Villar C. J., Llaneza J., Mendoza M. C. Prédominance et dispersion des plasmides conférant la résistance á la fosfomycine chez des entérobactéries. Pathol Biol (Paris) 1984 Sep;32(7):755–758. [PubMed] [Google Scholar]
  22. Hendlin D., Stapley E. O., Jackson M., Wallick H., Miller A. K., Wolf F. J., Miller T. W., Chaiet L., Kahan F. M., Foltz E. L. Phosphonomycin, a new antibiotic produced by strains of streptomyces. Science. 1969 Oct 3;166(3901):122–123. doi: 10.1126/science.166.3901.122. [DOI] [PubMed] [Google Scholar]
  23. Hopwood D. A. The Leeuwenhoek lecture, 1987. Towards an understanding of gene switching in Streptomyces, the basis of sporulation and antibiotic production. Proc R Soc Lond B Biol Sci. 1988 Nov 22;235(1279):121–138. doi: 10.1098/rspb.1988.0067. [DOI] [PubMed] [Google Scholar]
  24. Höger P. H., Seger R. A., Schaad U. B., Hitzig W. H. Chronic granulomatous disease: uptake and intracellular activity of fosfomycin in granulocytes. Pediatr Res. 1985 Jan;19(1):38–44. doi: 10.1203/00006450-198501000-00011. [DOI] [PubMed] [Google Scholar]
  25. Iizuka M., Inoue Y., Murata K., Kimura A. Purification and some properties of glutathione S-transferase from Escherichia coli B. J Bacteriol. 1989 Nov;171(11):6039–6042. doi: 10.1128/jb.171.11.6039-6042.1989. [DOI] [PMC free article] [PubMed] [Google Scholar]
  26. Inouye S., Niizato T., Komiya I., Yuda Y., Yamada Y. Mode of protective action of fosfomycin against dibekacin-induced nephrotoxicity in the dehydrated rats. J Pharmacobiodyn. 1982 Dec;5(12):941–950. doi: 10.1248/bpb1978.5.941. [DOI] [PubMed] [Google Scholar]
  27. Kadner R. J., Winkler H. H. Isolation and characterization of mutations affecting the transport of hexose phosphates in Escherichia coli. J Bacteriol. 1973 Feb;113(2):895–900. doi: 10.1128/jb.113.2.895-900.1973. [DOI] [PMC free article] [PubMed] [Google Scholar]
  28. Kahan F. M., Kahan J. S., Cassidy P. J., Kropp H. The mechanism of action of fosfomycin (phosphonomycin). Ann N Y Acad Sci. 1974 May 10;235(0):364–386. doi: 10.1111/j.1749-6632.1974.tb43277.x. [DOI] [PubMed] [Google Scholar]
  29. León J., García-Lobo J. M., Navas J., Ortiz J. M. Fosfomycin-resistance plasmids determine an intracellular modification of fosfomycin. J Gen Microbiol. 1985 Jul;131(7):1649–1655. doi: 10.1099/00221287-131-7-1649. [DOI] [PubMed] [Google Scholar]
  30. León J., García-Lobo J. M., Ortiz J. M. Fosfomycin inactivates its target enzyme in Escherichia coli cells carrying a fosfomycin resistance plasmid. Antimicrob Agents Chemother. 1983 Aug;24(2):276–278. doi: 10.1128/aac.24.2.276. [DOI] [PMC free article] [PubMed] [Google Scholar]
  31. León J., García-Lobo J. M., Ortiz J. M. Fosfomycin resistance plasmids do not affect fosfomycin transport into Escherichia coli. Antimicrob Agents Chemother. 1982 Apr;21(4):608–612. doi: 10.1128/aac.21.4.608. [DOI] [PMC free article] [PubMed] [Google Scholar]
  32. Llaneza J., Villar C. J., Salas J. A., Suarez J. E., Mendoza M. C., Hardisson C. Plasmid-mediated fosfomycin resistance is due to enzymatic modification of the antibiotic. Antimicrob Agents Chemother. 1985 Jul;28(1):163–164. doi: 10.1128/aac.28.1.163. [DOI] [PMC free article] [PubMed] [Google Scholar]
  33. López-Cabrera M., Pérez-González J. A., Heinzel P., Piepersberg W., Jiménez A. Isolation and nucleotide sequencing of an aminocyclitol acetyltransferase gene from Streptomyces rimosus forma paromomycinus. J Bacteriol. 1989 Jan;171(1):321–328. doi: 10.1128/jb.171.1.321-328.1989. [DOI] [PMC free article] [PubMed] [Google Scholar]
  34. Mannervik B., Danielson U. H. Glutathione transferases--structure and catalytic activity. CRC Crit Rev Biochem. 1988;23(3):283–337. doi: 10.3109/10409238809088226. [DOI] [PubMed] [Google Scholar]
  35. Marre R., Schulz E., Hedtke D., Sack K. Influence of fosfomycin and tobramycin on vancomycin-induced nephrotoxicity. Infection. 1985 Jul-Aug;13(4):190–192. doi: 10.1007/BF01642811. [DOI] [PubMed] [Google Scholar]
  36. Mendez F. J., Alvarez A. A., Mendoza M. C., Hardisson C. Antibacterial activity of fosmidomycin on chromosomic and plasmid-determined fosfomycin-resistant strains. Chemioterapia. 1985 Apr;4(2):170–175. [PubMed] [Google Scholar]
  37. Mendoza C., Garcia J. M., Llaneza J., Mendez F. J., Hardisson C., Ortiz J. M. Plasmid-determined resistance to fosfomycin in Serratia marcescens. Antimicrob Agents Chemother. 1980 Aug;18(2):215–219. doi: 10.1128/aac.18.2.215. [DOI] [PMC free article] [PubMed] [Google Scholar]
  38. Mendoza M. C., Teran F. J., Mendez F. J., Hardisson C. Molecular relationship among fosfomycin-resistant plasmids and clinical impact of fosfomycin resistance. Microbiologica. 1988 Oct;11(4):289–297. [PubMed] [Google Scholar]
  39. Navas J., García-Lobo J. M., León J., Ortíz J. M. Structural and functional analyses of the fosfomycin resistance transposon Tn2921. J Bacteriol. 1985 Jun;162(3):1061–1067. doi: 10.1128/jb.162.3.1061-1067.1985. [DOI] [PMC free article] [PubMed] [Google Scholar]
  40. Obaseiki-Ebor E. E. Activity of fosfomycin and R-plasmid conferring fosfomycin resistance among some clinical bacteria isolates in Nigeria. Chemotherapy. 1986;32(1):31–36. doi: 10.1159/000238386. [DOI] [PubMed] [Google Scholar]
  41. Olay T., Rodríguez A., Oliver L. E., Vicente M. V., Quecedo M. C. Interaction of fosfomycin with other antimicrobial agents: in vitro and in vivo studies. J Antimicrob Chemother. 1978 Nov;4(6):569–576. doi: 10.1093/jac/4.6.569. [DOI] [PubMed] [Google Scholar]
  42. Rice L. B., Eliopoulos G. M., Moellering R. C., Jr In vitro synergism between daptomycin and fosfomycin against Enterococcus faecalis isolates with high-level gentamicin resistance. Antimicrob Agents Chemother. 1989 Apr;33(4):470–473. doi: 10.1128/aac.33.4.470. [DOI] [PMC free article] [PubMed] [Google Scholar]
  43. Sicilia T., Estévez E., Rodríguez A. Fosfomycin penetration into the cerebrospinal fluid of patients with bacterial meningitis. Chemotherapy. 1981;27(6):405–413. doi: 10.1159/000238009. [DOI] [PubMed] [Google Scholar]
  44. Smeyers Y. G., Hernandez-Laguna A., Von Carstenn-Lichterfelde C. Quantum mechanical calculations useful for determining the mechanism of action of fosfomycin. J Pharm Sci. 1983 Sep;72(9):1011–1014. doi: 10.1002/jps.2600720910. [DOI] [PubMed] [Google Scholar]
  45. Smeyers Y. G., Herńandez Laguna A., Romero-Sánchez F. J., Fernández-Ibañez M., Galvez-Ruano E., Arias-Pérez S. Self-consistent field-molecular orbital (SCF-MO) calculations and nuclear magnetic resonance measurements for fosfomycin and related compounds. J Pharm Sci. 1987 Sep;76(9):753–756. doi: 10.1002/jps.2600760915. [DOI] [PubMed] [Google Scholar]
  46. Thompson C. J., Gray G. S. Nucleotide sequence of a streptomycete aminoglycoside phosphotransferase gene and its relationship to phosphotransferases encoded by resistance plasmids. Proc Natl Acad Sci U S A. 1983 Sep;80(17):5190–5194. doi: 10.1073/pnas.80.17.5190. [DOI] [PMC free article] [PubMed] [Google Scholar]
  47. Tsuruoka T., Yamada Y. Charactertization of spontaneous fosfomycin (phosphonomycin)-resistant cells of Escherichia coli B in vitro. J Antibiot (Tokyo) 1975 Nov;28(11):906–911. doi: 10.7164/antibiotics.28.906. [DOI] [PubMed] [Google Scholar]
  48. Utsui Y., Ohya S., Magaribuchi T., Tajima M., Yokota T. Antibacterial activity of cefmetazole alone and in combination with fosfomycin against methicillin- and cephem-resistant Staphylococcus aureus. Antimicrob Agents Chemother. 1986 Dec;30(6):917–922. doi: 10.1128/aac.30.6.917. [DOI] [PMC free article] [PubMed] [Google Scholar]
  49. Venkateswaran P. S., Wu H. C. Isolation and characterization of a phosphonomycin-resistant mutant of Escherichia coli K-12. J Bacteriol. 1972 Jun;110(3):935–944. doi: 10.1128/jb.110.3.935-944.1972. [DOI] [PMC free article] [PubMed] [Google Scholar]
  50. Villar C. J., Hardisson C., Suárez J. E. Cloning and molecular epidemiology of plasmid-determined fosfomycin resistance. Antimicrob Agents Chemother. 1986 Feb;29(2):309–314. doi: 10.1128/aac.29.2.309. [DOI] [PMC free article] [PubMed] [Google Scholar]
  51. Walker M. S., Walker J. B. Streptomycin biosynthesis and metabolism. Enzymatic phosphorylation of dihydrostreptobiosamine moieties of dihydro-streptomycin-(streptidino) phosphate and dihydrostreptomycin by Streptomyces extracts. J Biol Chem. 1970 Dec 25;245(24):6683–6689. [PubMed] [Google Scholar]
  52. Zilhao R., Courvalin P. Nucleotide sequence of the fosB gene conferring fosfomycin resistance in Staphylococcus epidermidis. FEMS Microbiol Lett. 1990 Mar 15;56(3):267–272. doi: 10.1016/s0378-1097(05)80052-7. [DOI] [PubMed] [Google Scholar]

Articles from Antimicrobial Agents and Chemotherapy are provided here courtesy of American Society for Microbiology (ASM)

RESOURCES