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. 1991 May;35(5):983–985. doi: 10.1128/aac.35.5.983

Modulation of the intestinal flora of mice by treatment with aztreonam and tigemonam.

M L van Ogtrop 1, H F Guiot 1, H Mattie 1, E van Strijen 1, B R Sekh 1, R van Furth 1
PMCID: PMC245140  PMID: 1854181

Abstract

Oral and parenteral administration of aztreonam and oral administration of tigemonam to conventional mice caused a decrease in the number of aerobic gram-negative rods in the feces. Oral treatment with high doses of aztreonam (greater than or equal to 25 mg/kg/day) and tigemonam (100 mg/kg/day) adversely influenced colonization resistance, whereas oral treatment with lower doses of the monobactams or parenteral treatment with aztreonam did not.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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