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. 1991 Sep;35(9):1943–1945. doi: 10.1128/aac.35.9.1943

Species identification and antibiotic susceptibility testing of enterococci isolated from hospitalized patients.

J W Gray 1, D Stewart 1, S J Pedler 1
PMCID: PMC245301  PMID: 1952875

Abstract

A total of 236 enterococci from hospitalized patients were identified to the species level, and their susceptibilities to 11 antibiotics were determined. Overall, 195 (82.6%) and 38 (16.1%) isolates were identified as Enterococcus faecalis and E. faecium, respectively, but the species distribution as determined from blood culture isolates differed markedly. A total of 27 (63.2%) E. faecium isolates, but no E. faecalis strains, were ampicillin resistant (MIC, greater than 8 micrograms/ml). High-level gentamicin resistance (MIC, greater than 500 micrograms/ml) was found in 8.2% of E. faecalis isolates but was not seen in other species.

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Selected References

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  1. Acar J. F., Buu-Hoi A. Y. Resistance patterns of important gram-positive pathogens. J Antimicrob Chemother. 1988 Apr;21 (Suppl 100):41–47. doi: 10.1093/jac/21.suppl_c.41. [DOI] [PubMed] [Google Scholar]
  2. Barry A. L., Jones R. N. In-vitro activities of temafloxacin, tosufloxacin (A-61827) and five other fluoroquinolone agents. J Antimicrob Chemother. 1989 Apr;23(4):527–535. doi: 10.1093/jac/23.4.527. [DOI] [PubMed] [Google Scholar]
  3. Bartoloni A., Colao M. G., Orsi A., Dei R., Giganti E., Parenti F. In-vitro activity of vancomycin, teicoplanin, daptomycin, ramoplanin, MDL 62873 and other agents against staphylococci, enterococci and Clostridium difficile. J Antimicrob Chemother. 1990 Nov;26(5):627–633. doi: 10.1093/jac/26.5.627. [DOI] [PubMed] [Google Scholar]
  4. Bush L. M., Calmon J., Cherney C. L., Wendeler M., Pitsakis P., Poupard J., Levison M. E., Johnson C. C. High-level penicillin resistance among isolates of enterococci. Implications for treatment of enterococcal infections. Ann Intern Med. 1989 Apr 1;110(7):515–520. doi: 10.7326/0003-4819-110-7-515. [DOI] [PubMed] [Google Scholar]
  5. Cercenado E., García-Leoni M. E., Rodeño P., Rodríguez-Créixems M. Ampicillin-resistant enterococci. J Clin Microbiol. 1990 Apr;28(4):829–829. doi: 10.1128/jcm.28.4.829-.1990. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Chen H. Y. Resistance of enterococci to antibiotic combinations. J Antimicrob Chemother. 1986 Jul;18(1):1–4. doi: 10.1093/jac/18.1.1. [DOI] [PubMed] [Google Scholar]
  7. Courvalin P. Resistance of enterococci to glycopeptides. Antimicrob Agents Chemother. 1990 Dec;34(12):2291–2296. doi: 10.1128/aac.34.12.2291. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Edwards R., Greenwood D. Antibiotic resistance in enterococci in Nottingham. J Antimicrob Chemother. 1990 Jul;26(1):155–156. doi: 10.1093/jac/26.1.155. [DOI] [PubMed] [Google Scholar]
  9. Eliopoulos G. M., Wennersten C., Zighelboim-Daum S., Reiszner E., Goldmann D., Moellering R. C., Jr High-level resistance to gentamicin in clinical isolates of Streptococcus (Enterococcus) faecium. Antimicrob Agents Chemother. 1988 Oct;32(10):1528–1532. doi: 10.1128/aac.32.10.1528. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Facklam R. R., Collins M. D. Identification of Enterococcus species isolated from human infections by a conventional test scheme. J Clin Microbiol. 1989 Apr;27(4):731–734. doi: 10.1128/jcm.27.4.731-734.1989. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Gullberg R. M., Homann S. R., Phair J. P. Enterococcal bacteremia: analysis of 75 episodes. Rev Infect Dis. 1989 Jan-Feb;11(1):74–85. doi: 10.1093/clinids/11.1.74. [DOI] [PubMed] [Google Scholar]
  12. Hoffmann S. A., Moellering R. C., Jr The enterococcus: "putting the bug in our ears". Ann Intern Med. 1987 May;106(5):757–761. doi: 10.7326/0003-4819-106-5-757. [DOI] [PubMed] [Google Scholar]
  13. Jones R. N., Barry A. L., Thornsberry C. In-vitro studies of meropenem. J Antimicrob Chemother. 1989 Sep;24 (Suppl A):9–29. doi: 10.1093/jac/24.suppl_a.9. [DOI] [PubMed] [Google Scholar]
  14. Kim M. J., Weiser M., Gottschall S., Randall E. L. Identification of Streptococcus faecalis and Streptococcus faecium and susceptibility studies with newly developed antimicrobial agents. J Clin Microbiol. 1987 May;25(5):787–790. doi: 10.1128/jcm.25.5.787-790.1987. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. King A., Shannon K., Phillips I. The in-vitro activities of enoxacin and ofloxacin compared with that of ciprofloxacin. J Antimicrob Chemother. 1985 May;15(5):551–558. doi: 10.1093/jac/15.5.551. [DOI] [PubMed] [Google Scholar]
  16. Krogstad D. J., Pargwette A. R. Defective killing of enterococci: a common property of antimicrobial agents acting on the cell wall. Antimicrob Agents Chemother. 1980 Jun;17(6):965–968. doi: 10.1128/aac.17.6.965. [DOI] [PMC free article] [PubMed] [Google Scholar]
  17. Moellering R. C., Jr, Korzeniowski O. M., Sande M. A., Wennersten C. B. Species-specific resistance to antimocrobial synergism in Streptococcus faecium and Streptococcus faecalis. J Infect Dis. 1979 Aug;140(2):203–208. doi: 10.1093/infdis/140.2.203. [DOI] [PubMed] [Google Scholar]
  18. Murray B. E., Church D. A., Wanger A., Zscheck K., Levison M. E., Ingerman M. J., Abrutyn E., Mederski-Samoraj B. Comparison of two beta-lactamase-producing strains of Streptococcus faecalis. Antimicrob Agents Chemother. 1986 Dec;30(6):861–864. doi: 10.1128/aac.30.6.861. [DOI] [PMC free article] [PubMed] [Google Scholar]
  19. Oster S. E., Chirurgi V. A., Goldberg A. A., Aiken S., McCabe R. E. Ampicillin-resistant enterococcal species in an acute-care hospital. Antimicrob Agents Chemother. 1990 Sep;34(9):1821–1823. doi: 10.1128/aac.34.9.1821. [DOI] [PMC free article] [PubMed] [Google Scholar]
  20. Patterson J. E., Zervos M. J. High-level gentamicin resistance in Enterococcus: microbiology, genetic basis, and epidemiology. Rev Infect Dis. 1990 Jul-Aug;12(4):644–652. doi: 10.1093/clinids/12.4.644. [DOI] [PubMed] [Google Scholar]
  21. Ruoff K. L., de la Maza L., Murtagh M. J., Spargo J. D., Ferraro M. J. Species identities of enterococci isolated from clinical specimens. J Clin Microbiol. 1990 Mar;28(3):435–437. doi: 10.1128/jcm.28.3.435-437.1990. [DOI] [PMC free article] [PubMed] [Google Scholar]
  22. Sapico F. L., Canawati H. N., Ginunas V. J., Gilmore D. S., Montgomerie J. Z., Tuddenham W. J., Facklam R. R. Enterococci highly resistant to penicillin and ampicillin: an emerging clinical problem? J Clin Microbiol. 1989 Sep;27(9):2091–2095. doi: 10.1128/jcm.27.9.2091-2095.1989. [DOI] [PMC free article] [PubMed] [Google Scholar]
  23. Shlaes D. M., Levy J., Wolinsky E. Enterococcal bacteremia without endocarditis. Arch Intern Med. 1981 Apr;141(5):578–581. [PubMed] [Google Scholar]
  24. Smyth E. G., Stevens P. J., Holliman R. E. Prevalence and susceptibility of highly gentamicin resistant Enterococcus faecalis in a south London teaching hospital. J Antimicrob Chemother. 1989 Apr;23(4):633–639. doi: 10.1093/jac/23.4.633. [DOI] [PubMed] [Google Scholar]
  25. Warren R. E. Difficult streptococci. J Hosp Infect. 1988 Feb;11 (Suppl A):352–357. doi: 10.1016/0195-6701(88)90210-1. [DOI] [PubMed] [Google Scholar]
  26. Watanakunakorn C. Enterococci from blood cultures during 1980-1989: susceptibility to ampicillin, penicillin and vancomycin. J Antimicrob Chemother. 1990 Oct;26(4):602–604. doi: 10.1093/jac/26.4.602. [DOI] [PubMed] [Google Scholar]
  27. Zervos M. J., Dembinski S., Mikesell T., Schaberg D. R. High-level resistance to gentamicin in Streptococcus faecalis: risk factors and evidence for exogenous acquisition of infection. J Infect Dis. 1986 Jun;153(6):1075–1083. doi: 10.1093/infdis/153.6.1075. [DOI] [PubMed] [Google Scholar]

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