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. 1991 Oct;35(10):2125–2127. doi: 10.1128/aac.35.10.2125

Hygromycin B therapy of a murine coronaviral hepatitis.

G Macintyre 1, B Curry 1, F Wong 1, R Anderson 1
PMCID: PMC245338  PMID: 1662025

Abstract

Hepatitis caused by mouse hepatitis virus (MHV-A59), a murine coronavirus, is accompanied by direct infection and replication of virus within the liver. We demonstrate here that the aminoglycoside hygromycin B is able to eliminate MHV-A59 infection from mouse peritoneal macrophages and cultured liver cells in vitro and is also able to reduce levels of virus replication and necrotic liver foci in vivo.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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