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. 1991 Dec;35(12):2639–2642. doi: 10.1128/aac.35.12.2639

Inhibition of membrane potential-dependent amino acid transport by daptomycin.

N E Allen 1, W E Alborn Jr 1, J N Hobbs Jr 1
PMCID: PMC245446  PMID: 1687346

Abstract

Daptomycin inhibits the formation of UDP-N-acetylmuramyl-pentapeptide in Bacillus megaterium by inhibiting active transport of amino acids incorporated into the pentapeptide. The ability of daptomycin to inhibit active transport and peptidoglycan formation may be due to its ability to disrupt the transmembrane electrochemical gradient.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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