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. 1974 Jul;119(1):70–75. doi: 10.1128/jb.119.1.70-75.1974

Adenine Nucleotide Changes Associated with the Initiation of Sporulation in Bacillus subtilis

Keith W Hutchison 1, R S Hanson 1
PMCID: PMC245574  PMID: 4209776

Abstract

At the end of the exponential growth phase of Bacillus subtilis, there is a decrease in the energy level of the cell, whether expressed as adenosine triphosphate concentration or adenylate energy charge. Phosphate limitation of exponentially growing cells produces a similar decrease in the energy level of the cell, and sporulation is derepressed in the presence of 10 mM glucose. A reduction in the tryptophan concentration of the medium during phosphate limitation of the tryptophan auxotroph B. subtilis 168 prevented the decrease in energy charge. Cells do not sporulate under these conditions. Energy charge values of 0.30 to 0.35 found during sporulation do not lead to cell death.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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