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. 1974 Oct;120(1):390–393. doi: 10.1128/jb.120.1.390-393.1974

First Enzyme of Histidine Biosynthesis and Repression Control of Histidyl-Transfer Ribonucleic Acid Synthetase of Salmonella typhimurium

W G Coleman Jr a,1, L S Williams a
PMCID: PMC245774  PMID: 4609155

Abstract

The regulation of formation of histidyl-transfer ribonucleic acid (tRNA) synthetase was examined in strains of Salmonella typhimurium. When the first of the histidine-forming enzymes was wild type, the presence of 2-thiazolealanine in the growth medium prevented repression of histidyl-tRNA synthetase formation elicited by the addition of 1, 2, 4-triazole-3-alanine to these cultures. Conversely, thiazolealanine had no effect on repression of histidyl-tRNA synthetase formation by triazolealanine in hisG mutant strains. These data suggest a relationship between the control of histidyl-tRNA synthetase formation and the functional state of the histidine operon.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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