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. 1973 Jul;115(1):228–234. doi: 10.1128/jb.115.1.228-234.1973

Control of Arginine Biosynthesis in Escherichia coli: Inhibition of Arginyl-Transfer Ribonucleic Acid Synthetase Activity

A L Williams 1, D W Yem 1, E McGinnis 1, L S Williams 1
PMCID: PMC246234  PMID: 4577743

Abstract

In this study, we have extended our earlier observations indicating in vitro inhibition of arginyl-transfer ribonucleic acid synthetase (EC 6.1.13, arginine: soluble ribonucleic acid ligase, adenosine monophosphate) activity by the arginine biosynthetic precursors ornithine, citrulline, and argininosuccinate. Furthermore, we report evidence which suggest that this enzyme activity is inhibited by these arginine precursors in vivo and that this inhibition of activity results in a derepression of arginine biosynthesis.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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