Abstract
The following compounds or treatments have been shown to inhibit the oxidation of ammonia, but not the oxidation of hydroxylamine in cells of Nitrosomonas: (i) metal-binding agents such as allylthiourea or potassium cyanide; (ii) compounds such as SKF 525 which interact with cytochrome P-450 of mammalian microsomes; (iii) carbon monoxide; (iv) inhibitors of catalase, peroxidase, and amine oxidases such as thiosemicarbazide, ethylxanthate, and iproniazid, respectively; (v) uncouplers of oxidative phosphorylation such as m-chlorocarbonylcyanidephenylhydrazone; (vi) electron acceptors such as phenazine methosulfate; (vii) compounds such as methanol or N2O which react with free radicals; and (viii) illumination with 420 lux (5,000 foot candles) of light.
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Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Aleem M. I. Generation of reducing power in chemosynthesis. II. Energy-linked reduction of pyridine nucleotides in the chemoautotroph, Nitrosomonas europaea. Biochim Biophys Acta. 1966 Feb 14;113(2):216–224. doi: 10.1016/s0926-6593(66)80062-0. [DOI] [PubMed] [Google Scholar]
- Anderson J. R., Strumeyer D. H., Pramer D. Purification and properties of peroxidase from Nitrosomonas europaea. J Bacteriol. 1968 Jul;96(1):93–97. doi: 10.1128/jb.96.1.93-97.1968. [DOI] [PMC free article] [PubMed] [Google Scholar]
- CAMPBELL N. E., ALEEM M. I. THE EFFECT OF 2-CHLORO, 6-(TRICHLOROMETHYL) PYRIDINE ON THE CHEMOAUTOTROPHIC METABOLISM OF NITRIFYING BACTERIA. I. AMMONIA AND HYDROXYLAMINE OXIDATION BY NITROSOMONAS. Antonie Van Leeuwenhoek. 1965;31:124–136. doi: 10.1007/BF02045882. [DOI] [PubMed] [Google Scholar]
- Erickson R. H., Hooper A. B. Preliminary characterization of a variant co-binding heme protein from Nitrosomonas. Biochim Biophys Acta. 1972 Aug 17;275(2):231–244. doi: 10.1016/0005-2728(72)90044-8. [DOI] [PubMed] [Google Scholar]
- Erickson R. H., Hooper A. B., Terry K. R. Solubilization and purification of cytochrome 1 from Nitrosomonas. Biochim Biophys Acta. 1972;283(1):155–166. doi: 10.1016/0005-2728(72)90107-7. [DOI] [PubMed] [Google Scholar]
- Hackette S. L., Skye G. E., Burton C., Segel I. H. Characterization of an ammonium transport system in filamentous fungi with methylammonium-14C as the substrate. J Biol Chem. 1970 Sep 10;245(17):4241–4250. [PubMed] [Google Scholar]
- Hooper A. B. Biochemical basis of obligate autotrophy in Nitrosomonas europaea. J Bacteriol. 1969 Feb;97(2):776–779. doi: 10.1128/jb.97.2.776-779.1969. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Hooper A. B., Hansen J., Bell R. Characterization of glutamate dehydrogenase from the ammonia-oxidizing chemoautotroph Nitrosomonas europaea. J Biol Chem. 1967 Jan 25;242(2):288–296. [PubMed] [Google Scholar]
- Hooper A. B. Lag phase of ammonia oxidation by resting cells of Nitrosomonas eruopaea. J Bacteriol. 1969 Feb;97(2):968–969. doi: 10.1128/jb.97.2.968-969.1969. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Hooper A. B., Nason A. Characterization of hydroxylamine-cytochrome c reductase from the chemoautotrophs Nitrosomonas europaea and Nitrosocystis oceanus. J Biol Chem. 1965 Oct;240(10):4044–4057. [PubMed] [Google Scholar]
- Kalra V. K., Brodie A. F. Effect of N,N'-dicyclohexylcarbodiimide (DCCD) on electron transport particles of Mycobacterium phlei. Arch Biochem Biophys. 1971 Dec;147(2):653–659. doi: 10.1016/0003-9861(71)90424-3. [DOI] [PubMed] [Google Scholar]
- LEES H. The biochemistry of the nitrifying organisms. I. The ammonia oxidizing systems of Nitrosomonas. Biochem J. 1952 Sep;52(1):134–139. doi: 10.1042/bj0520134. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Rees M., Nason A. A P-450-like cytochrome and a soluble terminal oxidase identified as cytochrome o from Nitrosomonas europaea. Biochem Biophys Res Commun. 1965 Nov 8;21(3):248–256. doi: 10.1016/0006-291x(65)90279-2. [DOI] [PubMed] [Google Scholar]
- Suzuki I., Kwok S. C. Cell-free ammonia oxidation by Nitrosomonas europaea extracts: effects of polyamines, Mg2+ and albumin. Biochem Biophys Res Commun. 1970 Jun 5;39(5):950–955. doi: 10.1016/0006-291x(70)90416-x. [DOI] [PubMed] [Google Scholar]
- Tomlinson T. G., Boon A. G., Trotman C. N. Inhibition of nitrification in the activated sludge process of sewage disposal. J Appl Bacteriol. 1966 Aug;29(2):266–291. doi: 10.1111/j.1365-2672.1966.tb03477.x. [DOI] [PubMed] [Google Scholar]
- Watson S. W., Asbell M. A., Valois F. W. Ammonia oxidation by cell-free extracts of Nitrosocystis oceanus. Biochem Biophys Res Commun. 1970 Mar 27;38(6):1113–1119. doi: 10.1016/0006-291x(70)90354-2. [DOI] [PubMed] [Google Scholar]
- Yamanaka T. A cytochrome c peroxidase isolated from Thiobacillus novellus. Biochim Biophys Acta. 1972 Jul 12;275(1):74–82. doi: 10.1016/0005-2728(72)90025-4. [DOI] [PubMed] [Google Scholar]