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. 1973 Sep;115(3):1145–1150. doi: 10.1128/jb.115.3.1145-1150.1973

Tyrosine and Phenylalanine Biosynthesis in Escherichia coli K-12: Complementation Between Different tyrR Alleles

S W K Im 1, J Pittard 1
PMCID: PMC246364  PMID: 4580560

Abstract

Dominance tests in diploids have confirmed that the product of the tyrR gene is involved in a negative control system affecting the synthesis of both 3-deoxy-d-arabinoheptulosonic acid 7-phosphate (DAHP) synthetase (tyr) and DAHP synthetase (phe). Some tyrR mutants are derepressed for the synthesis of both DAHP synthetase (tyr) and (phe), whereas others are derepressed for the synthesis of DAHP synthetase (tyr) but overrepressed for the synthesis of DAHP synthetase (phe). Complementation tests between these alleles confirm that they are in the same cistron. The allele causing overrepression of enzyme synthesis is dominant over both the wild type and the derepressing allele in diploids.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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