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. 1973 Dec;116(3):1267–1272. doi: 10.1128/jb.116.3.1267-1272.1973

Production of Volatile Nitrogenous Compounds from the Degradation of Streptomycin by Pseudomonas maltophilia1

John J Fenton a,2, Harold H Harsch a,3, Dolph Klein a,4
PMCID: PMC246483  PMID: 4752939

Abstract

Ammonia, methylamine, and pyridine were detected in broth filtrates of a streptomycin-degrading strain of Pseudomonas maltophilia during growth on streptomycin as a sole carbon and nitrogen source. Ammonia and methylamine, quantitatively measured by conversion to chromophores with picryl sulfonic acid, were found to accumulate in broth, whereas pyridine concentration increased in the early stages of streptomycin degradation and then decreased as the degradation of the antibiotic neared completion. Exogenous pyridine was metabolized by washed-cell suspensions. Use of N-streptomycin-methyl-14C showed that the methylamine arose from the N-l-glucosamine-methyl moiety of streptomycin. Methylamine was an end product and was not further metabolized by cells.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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