Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Model of the variation in observed values of ΔCpITC as the center of a 30° experimental window moves across temperature. The model is based on single strand melting data for the component strands of duplex D-I in 10 mM NaHEPES, pH 7.5, and 1.0 M added NaCl. Dashed lines show the pronounced contribution of single strand melting to the observed ΔCp within the temperature range usually targeted for structure prediction, 25–37 °C.
