Abstract
Thirty patients with chronic pancreatitis (mostly calcific) were tested for glucose tolerance and serum insulin response to glucose loading. The responses were very variable and the insulin values did not clearly relate to the ‘glucose-tolerance-status’. Some subjects had low insulin levels throughout, some had average to high fasting levels without further response, and some showed an excellent rise of insulin level after glucose.
No antibodies to insulin could be found in seven patients. Synalbumin antagonist was present at 1·25% in five out of twelve patients tested.
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Selected References
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- BANK S., MARKS I. N., MOSHAL M. G., EFRON G., SILBER R. THE PANCREATIC-FUNCTION TEST--METHOD AND NORMAL VALUES. S Afr Med J. 1963 Oct 19;37:1061–1066. [PubMed] [Google Scholar]
- Bank S. The management of diabetes in the underprivileged, with special reference to pancreatic diabetes. S Afr Med J. 1966 Apr 23;40(15):342–346. [PubMed] [Google Scholar]
- HALES C. N., RANDLE P. J. Immunoassay of insulin with insulin-antibody precipitate. Biochem J. 1963 Jul;88:137–146. doi: 10.1042/bj0880137. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Keller P., Bank S., Jackson W. P., Marks I. N., O'Reilly I. G. Plasma-insulin levels in "pancreatic diabetes". Lancet. 1965 Dec 11;2(7424):1211–1213. doi: 10.1016/s0140-6736(65)90635-5. [DOI] [PubMed] [Google Scholar]
- MARKS I. N., BANK S. TREATMENT OF PANCREATIC DIABETES. Mod Treat. 1965 May;2:471–476. [PubMed] [Google Scholar]
- YALOW R. S., BERSON S. A. Immunologic aspects of insulin. Am J Med. 1961 Dec;31:882–891. doi: 10.1016/0002-9343(61)90030-4. [DOI] [PubMed] [Google Scholar]