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. 1971 Oct;47(552):644–647. doi: 10.1136/pgmj.47.552.644

The use of amiloride hydrochloride in the correction of hypokalaemic alkalosis induced by diuretics

A C Antcliff, M Hamilton, D G Beevers, J E Harpur
PMCID: PMC2467317  PMID: 5158837

Abstract

Amiloride hydrochloride is a very potent drug for correcting the profound hypokalaemia and metabolic alkalosis that is induced by thiazide and other diuretics. No potassium supplements are necessary.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. GINSBERG D. J., SAAD A., GABUZDA G. J. METABOLIC STUDIES WITH THE DIURETIC TRIAMTERENE IN PATIENTS WITH CIRRHOSIS AND ASCITES. N Engl J Med. 1964 Dec 10;271:1229–1235. doi: 10.1056/NEJM196412102712402. [DOI] [PubMed] [Google Scholar]
  2. Gombos E. A., Freis E. D., Moghadam A. Effects of MK-870 in normal subjects and hypertensive patients. N Engl J Med. 1966 Dec 1;275(22):1215–1220. doi: 10.1056/NEJM196612012752202. [DOI] [PubMed] [Google Scholar]
  3. Paterson J. W., Dollery C. T., Haslam R. M. Amiloride hydrochloride in hypertensive patients. Br Med J. 1968 Feb 17;1(5589):422–423. doi: 10.1136/bmj.1.5589.422. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. SHALDON S., RYDER J. A. Use of a pteridine diuretic (tri-amterene) in treatment of hepatic ascites. Br Med J. 1962 Sep 22;2(5307):764–767. doi: 10.1136/bmj.2.5307.764. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Senewiratne B., Sherlock S. Amiloride ('MK 870') in patients with ascites due to cirrhosis of the liver. Lancet. 1968 Jan 20;1(7534):120–122. doi: 10.1016/s0140-6736(68)92725-6. [DOI] [PubMed] [Google Scholar]
  6. Singh B. N., Richmond D. E., Wilson J. D., Simmonds H. A., North J. D. Evaluation of MK-870: a new potassium-sparing diuretic. Br Med J. 1967 Jan 21;1(5533):143–146. doi: 10.1136/bmj.1.5533.143. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Surveyor I., Saunders R. A. Amiloride and plasma-potassium. Lancet. 1968 Aug 31;2(7566):516–517. doi: 10.1016/s0140-6736(68)90679-x. [DOI] [PubMed] [Google Scholar]
  8. Wilson J. D., Richmond D. E., Simmonds H. A., North J. D. MK 870: a new potassium-sparing diuretic. N Z Med J. 1966 Aug;65(408):505–511. [PubMed] [Google Scholar]

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