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. 1971 Nov;108(2):874–884. doi: 10.1128/jb.108.2.874-884.1971

Chemical Characterization of a New Surface Antigenic Polysaccharide from a Mutant of Staphylococcus aureus

Teresa C M Wu 1, James T Park 1
PMCID: PMC247155  PMID: 5001874

Abstract

A mutant of Staphylococcus aureus H was isolated by virtue of its inability to agglutinate with antibodies against teichoic acid of S. aureus. Immunological studies revealed that the mutant, S. aureus T, possessed a new surface antigen in addition to having the antigenic determinant of the wild-type strain, the ribitol teichoic acid. The presence of this additional surface component rendered strain T resistant to staphylococcal typing phages, presumably by masking the phage-receptor sites. The polymer was separated from teichoic acid by chromatography on diethylaminoethyl cellulose and was shown to be composed of two amino sugars, N-acetyl-d-fucosamine and N-acetyl-d-mannosamin uronic acid.

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Selected References

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