Skip to main content
Journal of Bacteriology logoLink to Journal of Bacteriology
. 1971 Dec;108(3):1422–1423. doi: 10.1128/jb.108.3.1422-1423.1971

Alkaline Sucrose Gradient Sedimentation of Chromosomal Deoxyribonucleic Acid from Escherichia coli PolA+ and PolA Strains During Thymine Starvation

Steven G Sedgwick 1, Bryn A Bridges 1
PMCID: PMC247235  PMID: 4945202

Abstract

Single-strand breaks were not detected in the deoxyribonucleic acid of Escherichia coli after thymine starvation for up to 180 min, even in a sensitive PolA strain.

Full text

PDF
1422

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Baker M. L., Hewitt R. R. Influence of thymine starvation on the integrity of deoxyribonucleic acid in Escherichia coli. J Bacteriol. 1971 Mar;105(3):733–738. doi: 10.1128/jb.105.3.733-738.1971. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Cohen S. S., Barner H. D. STUDIES ON UNBALANCED GROWTH IN ESCHERICHIA COLI. Proc Natl Acad Sci U S A. 1954 Oct;40(10):885–893. doi: 10.1073/pnas.40.10.885. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. De Lucia P., Cairns J. Isolation of an E. coli strain with a mutation affecting DNA polymerase. Nature. 1969 Dec 20;224(5225):1164–1166. doi: 10.1038/2241164a0. [DOI] [PubMed] [Google Scholar]
  4. Kato T., Kondo S. Genetic and molecular characteristics of X-ray-sensitive mutants of Escherichia coli defective in repair synthesis. J Bacteriol. 1970 Nov;104(2):871–881. doi: 10.1128/jb.104.2.871-881.1970. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. MENNIGMANN H. D., SZYBALSKI W. Molecular mechanism of thymine-less death. Biochem Biophys Res Commun. 1962 Nov 27;9:398–404. doi: 10.1016/0006-291x(62)90023-2. [DOI] [PubMed] [Google Scholar]
  6. McGrath R. A., Williams R. W. Reconstruction in vivo of irradiated Escherichia coli deoxyribonucleic acid; the rejoining of broken pieces. Nature. 1966 Oct 29;212(5061):534–535. doi: 10.1038/212534a0. [DOI] [PubMed] [Google Scholar]
  7. Reichenbach D. L., Schaiberger G. E., Sallman B. The effect of thymine starvation on chromosomal structure of Escherichia coli JG-151. Biochem Biophys Res Commun. 1971 Jan 8;42(1):23–30. doi: 10.1016/0006-291x(71)90356-1. [DOI] [PubMed] [Google Scholar]
  8. Town C. D., Smith K. C., Kaplan H. S. DNA polymerase required for rapid repair of x-ray--induced DNA strand breaks in vivo. Science. 1971 May 21;172(3985):851–854. doi: 10.1126/science.172.3985.851. [DOI] [PubMed] [Google Scholar]
  9. Walker J. R. Thymine Starvation and Single-Strand Breaks in Chromosomal Deoxyribonucleic acid of Escherichia coli. J Bacteriol. 1970 Dec;104(3):1391–1392. doi: 10.1128/jb.104.3.1391-1392.1970. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from Journal of Bacteriology are provided here courtesy of American Society for Microbiology (ASM)

RESOURCES