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. 1972 Jan;109(1):262–265. doi: 10.1128/jb.109.1.262-265.1972

Loss of the Penicillinase Plasmid After Treatment of Staphylococcus aureus with Sodium Dodecyl Sulfate

Stephen A Sonstein 1, J N Baldwin 1
PMCID: PMC247275  PMID: 5057770

Abstract

Two strains of Staphylococcus aureus (PC1 and 196E), when grown in medium containing 0.002% sodium dodecyl sulfate (SDS), showed from 96.1 to 100% loss of the ability to produce penicillinase. Resistance to cadmium and zinc was lost concomitantly with the ability to produce penicillinase. A comparison of the rate of curing by SDS with the curing effects exerted by elevated temperature and ethidium bromide suggested that SDS is a more effective plasmid curing agent for susceptible strains of S. aureus than methods in use at present.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Baldwin J. N., Strickland R. H., Cox M. F. Some properties of the beta-lactamase genes in Staphylococcus epidermidis. Appl Microbiol. 1969 Oct;18(4):628–630. doi: 10.1128/am.18.4.628-630.1969. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Baudens J. G., Gerbaud C. R., Chabbert Y. A. Conséquences de la disparition, sous l'influence de l'Acriflavine, de la production de pénicillinase chez les souches résistantes hétérogènes a la méthicilline, oxacilline et céphalothine. Ann Inst Pasteur (Paris) 1965 Sep;109(3):372–383. [PubMed] [Google Scholar]
  3. Dulaney E. L. Activity of selected compounds against penicillinase producing Staphylococcus aureus. Trans N Y Acad Sci. 1970 Nov;32(7):843–857. doi: 10.1111/j.2164-0947.1970.tb02760.x. [DOI] [PubMed] [Google Scholar]
  4. HARMON S. A., BALDWIN J. N. NATURE OF THE DETERMINANT CONTROLLING PENICILLINASE PRODUCTION IN STAPHYLOCOCCUS AUREUS. J Bacteriol. 1964 Mar;87:593–597. doi: 10.1128/jb.87.3.593-597.1964. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. HASHIMOTO H., KONO K., MITSUHASHI S. ELIMINATION OF PENICILLIN RESISTANCE OF STAPHYLOCOCCUS AUREUS BY TREATMENT WITH ACRIFLAVINE. J Bacteriol. 1964 Jul;88:261–262. doi: 10.1128/jb.88.1.261-262.1964. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Inuzuka N., Nakamura S., Inuzuka M., Tomoeda M. Specific action of sodium dodecyl sulfate on the sex factor of Escherichia coli K-12 Hfr strains. J Bacteriol. 1969 Nov;100(2):827–835. doi: 10.1128/jb.100.2.827-835.1969. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. MAY J. W., HOUGHTON R. H., PERRET C. J. THE EFFECT OF GROWTH AT ELEVATED TEMPERATURES ON SOME HERITABLE PROPERTIES OF STAPHYLOCOCCUS AUREUS. J Gen Microbiol. 1964 Nov;37:157–169. doi: 10.1099/00221287-37-2-157. [DOI] [PubMed] [Google Scholar]
  8. NOVICK R. P. ANALYSIS BY TRANSDUCTION OF MUTATIONS AFFECTING PENICILLINASE FORMATION IN STAPHYLOCOCCUS AUREUS. J Gen Microbiol. 1963 Oct;33:121–136. doi: 10.1099/00221287-33-1-121. [DOI] [PubMed] [Google Scholar]
  9. NOVICK R. P., RICHMOND M. H. NATURE AND INTERACTIONS OF THE GENETIC ELEMENTS GOVERNING PENICILLINASE SYNTHESIS IN STAPHYLOCOCCUS AUREUS. J Bacteriol. 1965 Aug;90:467–480. doi: 10.1128/jb.90.2.467-480.1965. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Novick R. P., Roth C. Plasmid-linked resistance to inorganic salts in Staphylococcus aureus. J Bacteriol. 1968 Apr;95(4):1335–1342. doi: 10.1128/jb.95.4.1335-1342.1968. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. RICHMOND M. H. PURIFICATION AND PROPERTIES OF THE EXOPENICILLINASE FROM STAPHYLOCOCCUS AUREUS. Biochem J. 1963 Sep;88:452–459. doi: 10.1042/bj0880452. [DOI] [PMC free article] [PubMed] [Google Scholar]

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