Abstract
A naturally occurring R factor with constitutive pilus synthesis is described which resembles the sex factor F in compatibility and in restricting coliphage T7. Unlike F, it is not cured during growth with acridine orange. Results suggest that the R factor produces repressor of pilus synthesis, to which the operator is insensitive (i+oc). In this respect it differs from both the F factor (i−o+) and wild-type F-like R factors (i+o+).
Full text
PDF






Images in this article
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- ARBER W., DUSSOIX D. Host specificity of DNA produced by Escherichia coli. I. Host controlled modification of bacteriophage lambda. J Mol Biol. 1962 Jul;5:18–36. doi: 10.1016/s0022-2836(62)80058-8. [DOI] [PubMed] [Google Scholar]
- Anderson E. S. Influence of the delta transfer factor on the phage sensitivity of salmonellae. Nature. 1966 Nov 19;212(5064):795–799. doi: 10.1038/212795a0. [DOI] [PubMed] [Google Scholar]
- Bannister D., Glover S. W. Restriction and modification of bacteriophages by R+ strains of Escherichia coli K12. Biochem Biophys Res Commun. 1968 Mar 27;30(6):735–738. doi: 10.1016/0006-291x(68)90575-5. [DOI] [PubMed] [Google Scholar]
- Dowman J. E., Meynell G. G. Pleiotropic effects of de-repressed bacterial sex factors on colicinogeny and cell wall structure. Mol Gen Genet. 1970;109(1):57–68. doi: 10.1007/BF00334046. [DOI] [PubMed] [Google Scholar]
- Dubnau E., Stocker B. A. Behavior of three colicine factors and an R (drug resistance) factor in Hfr crosses in Salmonella typhimurium. Genet Res. 1967 Jun;9(3):283–297. doi: 10.1017/s0016672300010582. [DOI] [PubMed] [Google Scholar]
- Echols H. PROPERTIES OF F' STRAINS OF ESCHERICHIA COLI SUPERINFECTED WITH F-LACTOSE AND F-GALATOSE EPISOMES. J Bacteriol. 1963 Feb;85(2):262–268. doi: 10.1128/jb.85.2.262-268.1963. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Frydman A., Meynell E. Interactions between de-repressed F-like R factors and wild type colicin B factors: superinfection immunity and repressor susceptibility. Genet Res. 1969 Dec;14(3):315–322. doi: 10.1017/s0016672300002135. [DOI] [PubMed] [Google Scholar]
- Kameda M., Suzuki M., Nakajima T., Harada K., Mitsuhashi S. Genetic properties of a T factor and T-r recombinants. Jpn J Microbiol. 1970 Sep;14(5):339–349. doi: 10.1111/j.1348-0421.1970.tb00534.x. [DOI] [PubMed] [Google Scholar]
- Lawn A. M., Meynell E., Cooke M. Mixed infections with bacterial sex factors: sex pili of pure and mixed phenotype. Ann Inst Pasteur (Paris) 1971 Jan;120(1):3–8. [PubMed] [Google Scholar]
- Lawn A. M., Meynell E. Serotypes of sex pili. J Hyg (Lond) 1970 Dec;68(4):683–694. doi: 10.1017/s0022172400042625. [DOI] [PMC free article] [PubMed] [Google Scholar]
- MAEKELAE O., MAEKELAE P. H., SOIKKELI S. SEX-SPECIFICITY OF THE BACTERIOPHAGE T7. Ann Med Exp Biol Fenn. 1964;42:188–195. [PubMed] [Google Scholar]
- MITSUHASHI S., HARADA K., HASHIMOTO H., KAMEDA M., SUZUKI M. Combination of two types of transmissible drug-resistance factors in a host bacterium. J Bacteriol. 1962 Jul;84:9–16. doi: 10.1128/jb.84.1.9-16.1962. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Meynell E., Cooke M. Repressor-minus and operator-constitutive de-repressed mutants of F-like R factors: their effect on chromosomal transfer by HfrC. Genet Res. 1969 Dec;14(3):309–313. doi: 10.1017/s0016672300002123. [DOI] [PubMed] [Google Scholar]
- Meynell E., Datta N. The relation of resistance transfer factors to the F-factor (sex-factor) of Escherichia coli K12. Genet Res. 1966 Feb;7(1):134–140. doi: 10.1017/s0016672300009538. [DOI] [PubMed] [Google Scholar]
- Morrison T. G., Malamy M. H. Comparisons of F factors and R factors: existence of independent regulation groups in F factors. J Bacteriol. 1970 Jul;103(1):81–88. doi: 10.1128/jb.103.1.81-88.1970. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Reeve E. C., Braithwaite J. A. Fk-lac, an episome with unusual properties found in a wild strain of a Klebsiella species. Nature. 1970 Oct 10;228(5267):162–164. doi: 10.1038/228162a0. [DOI] [PubMed] [Google Scholar]
- Smith H. W., Gyles C. L. The relationship between different transmissible plasmids introduced by F into the same strain of Escherichia coli K12. J Gen Microbiol. 1970 Aug;62(3):227–285. doi: 10.1099/00221287-62-3-277. [DOI] [PubMed] [Google Scholar]
- WATANABE T. EPISOME-MEDIATED TRANSFER OF DRUG RESISTANCE IN ENTEROBACTERIACEAE. VI. HIGH-FREQUENCY RESISTANCE TRANSFER SYSTEM IN ESCHERICHIA COLI. J Bacteriol. 1963 Apr;85:788–794. doi: 10.1128/jb.85.4.788-794.1963. [DOI] [PMC free article] [PubMed] [Google Scholar]
- WATANABE T. Infective heredity of multiple drug resistance in bacteria. Bacteriol Rev. 1963 Mar;27:87–115. doi: 10.1128/br.27.1.87-115.1963. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Watanabe T. Evolutionary relationships of R factors with other episomes and plasmids. Fed Proc. 1967 Jan-Feb;26(1):23–28. [PubMed] [Google Scholar]
- Watanabe T., Ogata C. Episome-mediated transfer of drug resistance in Enterobacteriaceae. IX. Recombination of an R factor with F. J Bacteriol. 1966 Jan;91(1):43–50. doi: 10.1128/jb.91.1.43-50.1966. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Wolfowitz J. CONTRIBUTIONS TO INFORMATION THEORY. Proc Natl Acad Sci U S A. 1960 Apr;46(4):557–561. doi: 10.1073/pnas.46.4.557. [DOI] [PMC free article] [PubMed] [Google Scholar]