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. 1972 Mar;109(3):987–992. doi: 10.1128/jb.109.3.987-992.1972

Action of Haemophilus Endodeoxyribonuclease on Biologically Active Deoxyribonucleic Acid

Rosa Gromkova 1, Sol H Goodgal 1
PMCID: PMC247318  PMID: 4334766

Abstract

An enzyme similar to that described by Smith and Wilcox (15) for Haemophilus influenzae which attacks foreign deoxyribonucleic acid (DNA) but not its own has been isolated and purified from H. parainfluenzae. The enzyme degrades foreign DNA to limited sizes and can destroy the transforming activity of H. influenzae and Bacillus subtilis DNA. The enzyme can also destroy the biological activity of H. influenzae phage and prophage DNA. On the other hand, the H. influenzae endodeoxyribonuclease can destroy the transforming activity of H. parainfluenzae DNA but not its own DNA. It also attacks B. subtilis DNA and its transforming activity.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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