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Journal of Bacteriology logoLink to Journal of Bacteriology
. 1972 May;110(2):616–623. doi: 10.1128/jb.110.2.616-623.1972

Physiological Factors in the Regulation of Alkaline Phosphatase Synthesis in Escherichia coli

Adam S Wilkins a,1
PMCID: PMC247456  PMID: 4553839

Abstract

Alkaline phosphatase is induced in excess phosphate media by starvation either for pyrimidines or for guanine. Induction is observed both during starvation, after a lag period, and following a period of starvation. Induction is not caused by a lowering of the internal orthophosphate pool, but is linked to alterations in the levels of the nucleotide pools. Experiments with purine-requiring mutants suggest that phosphatase is induced in wild-type strains by an adenine nucleotide. Mutations in the phoR gene can produce differential responses to the different starvation regimes.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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