Abstract
Double mutants of Serratia marcescens resistant to isoleucine hydroxamate and α-aminobutyric acid accumulated large amounts of isoleucine in a salts-sugar medium and lacked both feedback inhibition and repression of the isoleucine biosynthesis.
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Selected References
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- Hatfield G. W., Burns R. O. Specific binding of leucyl transfer RNA to an immature form of L-threonine deaminase: its implications in repression. Proc Natl Acad Sci U S A. 1970 Aug;66(4):1027–1035. doi: 10.1073/pnas.66.4.1027. [DOI] [PMC free article] [PubMed] [Google Scholar]
- KISUMI M. Studies on the isoleucine fermentation. I. Screening of organisms and investigation of cultural conditions. J Biochem. 1962 Dec;52:390–399. doi: 10.1093/oxfordjournals.jbchem.a127635. [DOI] [PubMed] [Google Scholar]
- Kisumi M., Komatsubara S., Chibata I. Multivalent repression and genetic depression of isoleucine-valine biosynthetic enzymes in Serratia marcescens. J Bacteriol. 1971 Sep;107(3):824–827. doi: 10.1128/jb.107.3.824-827.1971. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Kisumi M., Komatsubara S., Chibata I. Valine accumulation by alpha-aminobutyric acid-resistant mutants of Serratia marcescens. J Bacteriol. 1971 May;106(2):493–499. doi: 10.1128/jb.106.2.493-499.1971. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Kisumi M., Komatsubara S., Sugiura M., Chibata I. Isoleucine hydroxamate, an isoleucine antagonist. J Bacteriol. 1971 Sep;107(3):741–745. doi: 10.1128/jb.107.3.741-745.1971. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Kisumi M., Komatsubara S., Sugiura M., Chibata I. Properties of isoleucine hydroxamate-resistant mutants of Serratia marcescens. J Gen Microbiol. 1971 Dec;69(3):291–297. doi: 10.1099/00221287-69-3-291. [DOI] [PubMed] [Google Scholar]
- RAMAKRISHNAN T., ADELBERG E. A. REGULATORY MECHANISMS IN THE BIOSYNTHESIS OF ISOLEUCINE AND VALINE. I. GENETIC DEREPRESSION OF ENZYME FORMATION. J Bacteriol. 1964 Mar;87:566–573. doi: 10.1128/jb.87.3.566-573.1964. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Reh M., Schlegel H. G. Die Biosynthese von Isoleucin und Valin in Hydrogenomonas H 16. Arch Mikrobiol. 1969;67(2):110–127. [PubMed] [Google Scholar]
- UMBARGER H. E., BROWN B. Isoleucine and valine metabolism in Escherichia coli. V. Antagonism between isoleucine and valine. J Bacteriol. 1955 Aug;70(2):241–248. doi: 10.1128/jb.70.2.241-248.1955. [DOI] [PMC free article] [PubMed] [Google Scholar]