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. 1966;34(3):357–361.

Ocular manifestations of vitamin-A deficiency in man*

D S McLaren, H A P C Oomen, H Escapini
PMCID: PMC2475981  PMID: 5296395

Abstract

Vitamin-A deficiency continues to be one of the most widely prevalent and devastating nutritional diseases of man. This is in spite of the discovery of vitamin A more than half a century ago and its now ready availability in inexpensive concentrated form. Lack of knowledge at many levels is the basis of this tragic situation, which may result in needless blindness and loss of life, especially among young children.

As a contribution to the alleviation of the problem, the present paper has as its object the provision, for the general and hospital physician in those countries where xerophthalmia is endemic, of adequate descriptive and pictorial information to enable him to make an accurate diagnosis of vitamin-A deficiency when he is presented with any stage of the ocular manifestations.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. DARBY W. J., McGANITY W. J., McLAREN D. S., PATON D., ALEMU Z., GEBRE-MEDHEN M. Bitot's spots and vitamin A deficiency. Public Health Rep. 1960 Aug;75:738–743. [PMC free article] [PubMed] [Google Scholar]
  2. DHANDA R. P. Electroretinography in night blindness and other vitamin A deficiencies. AMA Arch Ophthalmol. 1955 Dec;54(6):841–849. doi: 10.1001/archopht.1955.00930020847005. [DOI] [PubMed] [Google Scholar]
  3. HALASA A. H., MCLAREN D. S. THE REFRACTIVE STATE OF MALNOURISHED CHILDREN. Arch Ophthalmol. 1964 Jun;71:827–831. doi: 10.1001/archopht.1964.00970010843009. [DOI] [PubMed] [Google Scholar]
  4. McLAREN D. S. Involvement of the eye in protein malnutrition. Bull World Health Organ. 1958;19(2):303–314. [PMC free article] [PubMed] [Google Scholar]
  5. McLaren D. S., Shirajian E., Tchalian M., Khoury G. Xerophthalmia in Jordan. Am J Clin Nutr. 1965 Sep;17(3):117–130. doi: 10.1093/ajcn/17.3.117. [DOI] [PubMed] [Google Scholar]
  6. OOMEN H. A., MCLAREN D. S., ESCAPINI H. EPIDEMIOLOGY AND PUBLIC HEALTH ASPECTS OF HYPOVITAMINOSIS A. A GLOBAL SURVEY ON XEROPHTHALMIA. Trop Geogr Med. 1964 Dec;16:271–315. [PubMed] [Google Scholar]
  7. PATON D., McLAREN D. S. Bitot spots. Am J Ophthalmol. 1960 Oct;50:568–574. doi: 10.1016/0002-9394(60)90234-8. [DOI] [PubMed] [Google Scholar]

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