Skip to main content
Bulletin of the World Health Organization logoLink to Bulletin of the World Health Organization
. 1966;35(5):675–680.

Phage resistance in Vibrio cholerae*

S Rizvi, A S Benenson
PMCID: PMC2476232  PMID: 5297802

Abstract

Mukerjee cholera phages are being extensively used in the classification of vibrios. However, the studies reported here show that phage-resistant mutants that are exactly like the parent strains in all characteristics except phage reactions can easily be obtained. For this reason phage reactions should be considered only as a marker and not as the final arbiter in vibrio classification, e.g., in attempting to identify the El Tor vibrio. Confirmatory evidence should always be sought.

It is also shown that routine phage work can be simplified by preparing phage-specific hosts and using them for the preparation of phage stocks without any fear of cross-contamination. The properties of phages prepared on the specific hosts are similar to those of phages prepared on the universal host.

Full text

PDF
675

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Demerec M, Fano U. Bacteriophage-Resistant Mutants in Escherichia Coli. Genetics. 1945 Mar;30(2):119–136. doi: 10.1093/genetics/30.2.119. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. FEELEY J. C. CLASSIFICATION OF VIBRIO CHOLERAE (VIBRIO COMMA), INCLUDING EL TOR VIBRIOS, BY INFRASUBSPECIFIC CHARACTERISTICS. J Bacteriol. 1965 Mar;89:665–670. doi: 10.1128/jb.89.3.665-670.1965. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. RIZVI S., HUQ M. I., BENENSON A. S. ISOLATION OF HEMAGGLUTINATIVE NON-EL TOR CHOLERA VIBRIOS. J Bacteriol. 1965 Mar;89:910–912. doi: 10.1128/jb.89.3.910-912.1965. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. SAYAMOV R. M. Treatment and prophylaxis of cholera with bacteriophage. Bull World Health Organ. 1963;28(3):361–367. [PMC free article] [PubMed] [Google Scholar]

Articles from Bulletin of the World Health Organization are provided here courtesy of World Health Organization

RESOURCES