Abstract
The conglutinative complement absorption test, using adult worm antigen (Schistosoma mansoni), was performed on the sera of 100 bilharziasis patients and of 111 non-infected individuals. If the sera that inhibit conglutination when diluted to 1: 40 or more are considered as reactive, the sensitivity of the test is 93.7% (six sera were anticomplementary). No reactive sera were found among the control group. In mice experimentally infected with S. mansoni, specific inhibition of conglutination began about the thirtieth day after exposure, when sexually mature schistosomes, migrating from the liver to the mesenteric vessels, were able to lay eggs.
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Selected References
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- CHAFFEE E. F., BAUMAN P. M., SHAPILO J. J. Diagnosis of schistosomiasis by complement-fixation. Am J Trop Med Hyg. 1954 Sep;3(5):905–913. doi: 10.4269/ajtmh.1954.3.905. [DOI] [PubMed] [Google Scholar]
- COOMBS A. M. The conglutination phenomenon. X. Conglutinin and immuno-conglutinin in guinea-pigs, pigs, donkeys, rats and mice. J Hyg (Lond) 1954 Dec;52(4):534–544. doi: 10.1017/s0022172400037025. [DOI] [PMC free article] [PubMed] [Google Scholar]
- INGRAM D. G., SOLTYS M. A. Immunity in trypanosomiasis. IV. Immuno-conglutinin in animals infected with Trypanosoma brucei. Parasitology. 1960 May;50:231–239. doi: 10.1017/s0031182000025312. [DOI] [PubMed] [Google Scholar]
- MARKS J., COOMBS R. R. The conglutination phenomenon. XI. Immunoconglutinin in human sera. J Hyg (Lond) 1957 Mar;55(1):81–90. doi: 10.1017/s0022172400061271. [DOI] [PMC free article] [PubMed] [Google Scholar]
- OLIVIER L., STIREWALT M. A. An efficient method for exposure of mice to cercariae of Schistosoma mansoni. J Parasitol. 1952 Feb;38(1):19–23. [PubMed] [Google Scholar]
- PAUTRIZEL R., TRIBOULEY J., SZERSNOVICZ F., DURET J. APPLICATION DE LA R'EACTION DE CONGLUTINATION AU DIAGNOSTIC DES BILHARZIOSES. Ann Inst Pasteur (Paris) 1964 Dec;107:863–872. [PubMed] [Google Scholar]
- PELLEGRINO J., de FREITAS J. Quantitative complement fixation test in schistosomiasis mansoni. Am J Trop Med Hyg. 1961 Jul;10:537–540. doi: 10.4269/ajtmh.1961.10.537. [DOI] [PubMed] [Google Scholar]
