Abstract
It has been traditional practice in many countries to let revaccination with BCG depend on the outcome of periodically repeated tuberculin testing. Acquired resistance to tuberculosis and tuberculin skin sensitivity are concomitant results of BCG vaccination, and it is apparently inferred that a waning resistance will be faithfully reflected in a waning tuberculin sensitivity. However, it has been demonstrated in recent years, both in man and in animals, that the waning of tuberculin sensitivity may be prevented merely by a repetition of the tuberculin test, while data presented in this and a following report indicate that tuberculin testing has no such influence on the course of BCG-induced resistance to tuberculosis.
Full text
PDF











Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- JESPERSEN A., BENTZON M. W., MAGNUSSON M. Development of tuberculin sensitivity and acquired resistance to tuberculosis in guinea pigs vaccinated with a small dose of BCG vaccine. Acta Pathol Microbiol Scand. 1962;54:291–304. doi: 10.1111/j.1699-0463.1962.tb01759.x. [DOI] [PubMed] [Google Scholar]
- MAGNUS K., EDWARDS L. B. The effect of repeated tuberculin testing on post-vaccination allergy; a preliminary note. Lancet. 1955 Sep 24;269(6891):643–644. doi: 10.1016/s0140-6736(55)92482-x. [DOI] [PubMed] [Google Scholar]
- MAGNUS K. Effect of intradermal tuberculin tests on BCG-induced allergy. Bull World Health Organ. 1957;17(2):249–254. [PMC free article] [PubMed] [Google Scholar]
- Tolderlund K., Bunch-Christensen K., Guld J. Duration of allergy and immunity in BCG-vaccinated guinea pigs. A five-year study. Bull World Health Organ. 1967;36(5):759–769. [PMC free article] [PubMed] [Google Scholar]