Abstract
The use of alkylating agents has been found to be a promising way of chemosterilizing mosquitos for control purposes. The investigation discussed in the present paper has shown that apholate (2,2,4,4,6,6-hexahydro-2,2,4,4,6,6-hexakis (1-aziridinyl)-1,3,5,2,4,6-triazatriphosphorine) can induce sterility rates of from 43% to 95% in Culex pipiens fatigans Wiedemann treated in the larval stage, and from 80% to 100% in C. fatigans treated in the adult stage; treatment in the pupal stage produced no significant sterility.
Of the methods of application of the apholate tested (immersion of larvae and pupae in water containing apholate, exposure of anaesthetized adults to residual deposits of apholate and dusting of anaesthetized adults with apholate powder), the dusting method was found to be effective.
Apholate induces sterility in both sexes. Females were affected much more when they were treated in the adult stage. The average number of eggs laid by a treated female was found to be reduced no matter whether the treatment was during the larval or the adult phase.
Male mosquitos chemosterilized by dusting were more competitive than normal males.
Full text
PDF
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- BERTRAM D. S. OBSERVATIONS ON THE CHEMOSTERILANT EFFECT OF AN ALKYLATING AGENT, THIO-TEPA, ON WILD-CAUGHT ANOPHELES GAMBIAE VAR. MELAS (THEO.) IN GAMBIA, WEST AFRICA, AND ON LABORATORY-BRED A. G. GAMBIAE GILES AND AEDES AEGYPTI (L.). Trans R Soc Trop Med Hyg. 1963 Sep;57:322–335. doi: 10.1016/0035-9203(63)90095-6. [DOI] [PubMed] [Google Scholar]
- DAME D. A., FORD H. R. CHEMOSTERILIZATION AND ITS PERMANENCY IN MOSQUITOES. Nature. 1964 Feb 15;201:733–734. doi: 10.1038/201733c0. [DOI] [PubMed] [Google Scholar]
- KNIPLING E. F. Sterile-male method of population control. Science. 1959 Oct 9;130(3380):902–904. doi: 10.1126/science.130.3380.902. [DOI] [PubMed] [Google Scholar]
- Labrecque G. C., Meifert D. W., Smith C. N. Mating Competitiveness of Chemosterilized and Normal Male House Flies. Science. 1962 May 4;136(3514):388–389. doi: 10.1126/science.136.3514.388. [DOI] [PubMed] [Google Scholar]
- WEIDHAAS D. E. Chemical sterilization of mosquitoes. Nature. 1962 Aug 25;195:786–787. doi: 10.1038/195786a0. [DOI] [PubMed] [Google Scholar]