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. 1967;36(2):263–274.

Pararosaniline pamoate (CI-403-A) in the treatment of Schistosoma japonicum infection in the Philippines*

T P Pesigan, T C Banzon, A T Santos, J Noseñas, R G Zabala
PMCID: PMC2476386  PMID: 5299751

Abstract

Trials have been carried out, first on a relatively small scale among patients in Manila and later on a larger scale among domiciliary patients in an area of endemic schistosomiasis in Leyte Province, Philippines, with various dosage schedules of pararosaniline pamoate (CI-403-A) to determine that drug's efficacy and optimum dosage against Schistosoma japonicum infection.

Given orally in gelatin capsules, the drug was well tolerated even in children, with few side-effects, and was both curative and suppressive when administered in a maximum dosage of 35-40 mg/kg body-weight per day for as many as 52 days spread over a total treatment period of 203 days.

The authors recommend its use for mass treatment, especially among schoolchildren, in combination with other established schistosomiasis control measures—health education, environmental sanitation, and snail control.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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