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. 1989 Feb;63(2):952–954. doi: 10.1128/jvi.63.2.952-954.1989

Mutations located on both F1 and F2 subunits of the Newcastle disease virus fusion protein confer resistance to neutralization with monoclonal antibodies.

C Neyt 1, J Geliebter 1, M Slaoui 1, D Morales 1, G Meulemans 1, A Burny 1
PMCID: PMC247772  PMID: 2463386

Abstract

The fusion gene sequence of six Newcastle disease virus escape mutants revealed that residues important for the integrity of antigenic site 1 and antigenic site 2 were located, respectively, on the F2 subunit and within the cysteine-rich domain of the F1 subunit. We further report the antibody-binding capacity of these mutants.

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Selected References

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