Skip to main content
Bulletin of the World Health Organization logoLink to Bulletin of the World Health Organization
. 1972;46(3):363–369.

Storage of chlorinated pesticides in human organs and tissues in Ferrara Province, Italy*

L Prati, R Pavanello, F Ghezzo
PMCID: PMC2480746  PMID: 4537854

Abstract

Residues of organochlorine compounds in human fat, liver, brain, kidney, and spleen were determined by gas chromatography. All the samples were obtained from residents of Ferrara Province, Italy, of both sexes and of ages ranging from 1 to 80 years who had no special exposure to insecticides. The following compounds were found: p,p′-DDE, o,p′-DDT, p,p′-DDT, HEOD, and heptachlor epoxide. DDT and its derivatives was found more frequently and at higher concentrations than the other compounds; the average weighted percentage ratio of DDE (as DDT) to total equivalent DDT in fat was 73.7%. The concentrations of residues in nonfatty tissues were considerably lower than in fatty tissue; in liver, and to a smaller extent in kidney, the average concentrations were higher than in other organs (brain and spleen). From comparisons of these results with those from other countries it appears that higher levels of chlorinated compounds are generally present in the Ferrara population.

Full text

PDF
363

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Duggan R. E. Pesticide residues in foods. Ann N Y Acad Sci. 1969;160(1):173–182. doi: 10.1111/j.1749-6632.1969.tb15838.x. [DOI] [PubMed] [Google Scholar]
  2. Durham W. F., Armstrong J. F., Quinby G. E. DDT and DDE content of complete prepared meals. Arch Environ Health. 1965 Nov;11(5):641–647. doi: 10.1080/00039896.1965.10664273. [DOI] [PubMed] [Google Scholar]
  3. Paccagnella B., Ghezzo F., Prati L., Fedrazzoni U., Belloni G. Epidemiological study of long-term effects of pesticides on human health. Bull World Health Organ. 1971;45(2):181–199. [PMC free article] [PubMed] [Google Scholar]
  4. de Vlieger M., Robinson J., Baldwin M. K., Crabtree A. N., van Dijk M. C. The organochlorine insecticide content of human tissues. Arch Environ Health. 1968 Nov;17(5):759–767. doi: 10.1080/00039896.1968.10665317. [DOI] [PubMed] [Google Scholar]

Articles from Bulletin of the World Health Organization are provided here courtesy of World Health Organization

RESOURCES