Skip to main content
NCBI home page
Bulletin of the World Health Organization logoLink to Bulletin of the World Health Organization
. 1972;46(4):473–476.

Antigenic relationships between the neuraminidases of influenza B virus

Pratima Chakraverty
PMCID: PMC2480781  PMID: 4538191

Abstract

Antigenic relationships between neuraminidases of influenza B viruses isolated from 1940 to 1968 were studied by neuraminidase-inhibition tests using hyperimmune rabbit antisera. The cross-reactions between the enzymes of influenza B viruses showed that some antigenic drift had occurred but that they are all related. From these results it is concluded that the differences between the neuraminidases of influenza B viruses are not sufficiently clear-cut to allow the viruses to be separated into subgroups.

Full text

PDF
473

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. ADA G. L., LIND P. E. AN IMMUNOLOGICAL STUDY OF AVIAN, VIRAL AND BACTERIAL NEURAMINIDASE BASED ON SPECIFIC INHIBITION OF ENZYME BY ANTIBODY. J Gen Microbiol. 1963 Aug;32:225–233. doi: 10.1099/00221287-32-2-225. [DOI] [PubMed] [Google Scholar]
  2. AMINOFF D. Methods for the quantitative estimation of N-acetylneuraminic acid and their application to hydrolysates of sialomucoids. Biochem J. 1961 Nov;81:384–392. doi: 10.1042/bj0810384. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Chakraverty P. Antigenic relationship between influenza B viruses. Bull World Health Organ. 1971;45(6):755–766. [PMC free article] [PubMed] [Google Scholar]
  4. Dowdle W. R., Coleman M. T., Hall E. C., Knez V. Properties of the Hong Kong influenza virus. Antigenic relationship of the Hong Kong virus haemagglutinin to that of other human influenza A viruses. Bull World Health Organ. 1969;41(3):419–424. [PMC free article] [PubMed] [Google Scholar]
  5. Easterday B., Laver W. G., Pereira H. G., Schild G. C. Antigenic composition of recombinant virus strains produced from human and avian influenza A viruses. J Gen Virol. 1969 Jul;5(1):83–91. doi: 10.1099/0022-1317-5-1-83. [DOI] [PubMed] [Google Scholar]
  6. HENNESSY A. V., MINUSE E., DAVENPORT F. M. A TWENTY-ONE-YEAR EXPERIENCE WITH ANTIGENIC VARIATION AMONG INFLUENZA B VIRUSES. J Immunol. 1965 Feb;94:301–306. [PubMed] [Google Scholar]
  7. Hoyle L. The chemical reactions of the haemagglutinins and neuraminidases of different strains of influenza viruses. I. Effect of reagents reacting with amino acids in the active centres. J Hyg (Lond) 1969 Jun;67(2):289–299. doi: 10.1017/s0022172400041693. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Laver W. G., Kilbourne E. D. Identification in a recombinant influenza virus of structural proteins derived from both parents. Virology. 1966 Nov;30(3):493–501. doi: 10.1016/0042-6822(66)90125-5. [DOI] [PubMed] [Google Scholar]
  9. MAYRON L. W., ROBERT B., WINZLER R. J., RAFELSON M. E., Jr Studies on the neuraminidase of influenza virus. I. Separation and some properties of the enzyme from Asian and PR8 strains. Arch Biochem Biophys. 1961 Mar;92:475–483. doi: 10.1016/0003-9861(61)90387-3. [DOI] [PubMed] [Google Scholar]
  10. Paniker C. K. Serological relationships between the neuraminidases in influenza viruses. J Gen Virol. 1968 May;2(3):385–394. doi: 10.1099/0022-1317-2-3-385. [DOI] [PubMed] [Google Scholar]
  11. Schild G. C., Newman R. W. Immunological relationships between the neuraminidases of human and animal influenza viruses. Bull World Health Organ. 1969;41(3):437–445. [PMC free article] [PubMed] [Google Scholar]
  12. Schild G. C., Pereira H. G. Characterization of the ribonucleoprotein and neuraminidase of influenza A viruses by immunodiffusion. J Gen Virol. 1969 Apr;4(3):355–363. doi: 10.1099/0022-1317-4-3-355. [DOI] [PubMed] [Google Scholar]
  13. Schild G. C., Pereira H. G., Schettler C. H. Neuraminidase in avin influenza A virus antigenically related to that of human A0 and A1 subtypes. Nature. 1969 Jun 28;222(5200):1299–1301. doi: 10.1038/2221299a0. [DOI] [PubMed] [Google Scholar]
  14. Seto JT BRZENIEK R., Rott R. Isolation of a low molecular weight sialidase (neuraminidase) from influenza virus. Biochim Biophys Acta. 1966 Feb 14;113(2):402–404. doi: 10.1016/s0926-6593(66)80081-4. [DOI] [PubMed] [Google Scholar]
  15. WARREN L. The thiobarbituric acid assay of sialic acids. J Biol Chem. 1959 Aug;234(8):1971–1975. [PubMed] [Google Scholar]
  16. Webster R. G., Laver W. G., Kilbourne E. D. Reactions of antibodies with surface antigens of influenza virus. J Gen Virol. 1968 Dec;3(3):315–326. doi: 10.1099/0022-1317-3-3-315. [DOI] [PubMed] [Google Scholar]

Articles from Bulletin of the World Health Organization are provided here courtesy of World Health Organization

RESOURCES