Skip to main content
NCBI home page
Bulletin of the World Health Organization logoLink to Bulletin of the World Health Organization
. 1972;47(1):37–48.

Some ultrastructural aspects of endemic nephropathy of the Balkans*

I Moraru, P Nicolescu, E Mandache, C Zosin, N Mănescu, A Schwarzkopf
PMCID: PMC2480803  PMID: 4538904

Abstract

Two renal biopsies selected from a large number of specimens taken by renal puncture from patients suffering from endemic nephropathy were studied by electron microscopy. Ultrastructural lesions were seen as electron-dense deposits in the walls of the glomerular capillaries, sometimes associated with glomerular proliferative processes. Such lesions, which are probably the early stages of this obscure renal disease, suggest that an auto-immune mechanism may be involved.

Full text

PDF
37

Images in this article

43Fig. 5
on p.43
39Fig. 1
on p.39
40Fig. 2
on p.40
44Fig. 6
on p.44
41Fig. 3
on p.41
45Fig. 7
on p.45
42Fig. 4
on p.42

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Bruckner I., Lăzărescu R. Problemele nefopatiei endemice. Med Interna (Bucur) 1967 Mar;19(3):259–267. [PubMed] [Google Scholar]
  2. Bulić F. Cîteva reflecţii privind problema etiologiei şi patogenezei nefropatiei endemice. Med Interna (Bucur) 1967 Mar;19(3):277–280. [PubMed] [Google Scholar]
  3. Burkholder P. M., Marchand A., Krueger R. P. Mixed membranous and proliferative glomerulonephritis. A correlative light, immunofluorescence, and electron microscopic study. Lab Invest. 1970 Nov;23(5):459–479. [PubMed] [Google Scholar]
  4. COCHRANE C. G., UNANUE E. R., DIXON F. J. A ROLE OF POLYMORPHONUCLEAR LEUKOCYTES AND COMPLEMENT IN NEPHROTOXIC NEPHRITIS. J Exp Med. 1965 Jul 1;122:99–116. doi: 10.1084/jem.122.1.99. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Gang N. F., Kalant N. Nephrotoxic serum nephritis. I. Chemical, morphologic, and functional changes in the glomerular basement membrane during the evolution of nephritis. Lab Invest. 1970 Jun;22(6):531–540. [PubMed] [Google Scholar]
  6. Gang N. F., Mautner W., Kalant N. Nephrotoxic serum nephritis. II. Chemical, morphologic, and functional correlates of glomerular basement membrane at the onset of proteinuria. Lab Invest. 1970 Aug;23(2):150–157. [PubMed] [Google Scholar]
  7. HALL P. W., 3rd, DAMMIN G. J., GRIGGS R. C., FAJGELJ A., ZIMONJIC B., GAON J. INVESTIGATION OF CHRONIC ENDEMIC NEPHROPATHY IN YUGOSLAVIA. II. RENAL PATHOLOGY. Am J Med. 1965 Aug;39:210–217. doi: 10.1016/0002-9343(65)90043-4. [DOI] [PubMed] [Google Scholar]
  8. MARKOVIC B., LEBEDEV S. ROLE 'ETIOPATHOG'ENIQUE DES SILICATES 'EROSIFS DANS LA N'EPHRITE END'EMIQUE. Presse Med. 1965 Feb 13;73:401–404. [PubMed] [Google Scholar]
  9. Markovic B. Substratum histopathologique de la néprite endémique. J Urol Nephrol (Paris) 1968 Oct-Nov;74(10):843–847. [PubMed] [Google Scholar]
  10. Paraschiv D., Petrescu G. H., Bömchis F. Aspecte anatomoclinice ale bolii de Ergheviţa din Raionul Turnu Severin. Med Interna (Bucur) 1967 Mar;19(3):313–323. [PubMed] [Google Scholar]
  11. Puhlev A. Nefropatia endemică în Bulgaria. Med Interna (Bucur) 1967 Mar;19(3):293–300. [PubMed] [Google Scholar]
  12. TANCEV I. PARTICULARIT A TILE CLINICE ALE NEFRITEI CRONICE ENDEMICE DIN RAIONUL VRA TA, BULGARIA. Med Interna (Bucur) 1963 Nov;15:1313–1318. [PubMed] [Google Scholar]
  13. Tonea T. Consideraţii asupra unor aspecte etiologice ale nefropatiei cronice endemice. II. Med Interna (Bucur) 1967 Mar;19(3):333–340. [PubMed] [Google Scholar]
  14. Tonea T. Consideraţii asupra unor aspecte etiologice ale nefropatiei cronice endemice. Notă preliminară. Med Interna (Bucur) 1966 Feb;18(2):149–158. [PubMed] [Google Scholar]
  15. Zosin C., Georgescu L., Manescu N., Sabo I., Schwarzkopf A., Vintilescu D. Aspects anatomo-cliniques de la néphropathie endémique balkanique. Sem Hop. 1966 Jan 14;42(3):194–201. [PubMed] [Google Scholar]
  16. Zosin C. Sindromul clinic şi biologic al nefropatiei endemice cronice. Med Interna (Bucur) 1967 Mar;19(3):269–275. [PubMed] [Google Scholar]

Articles from Bulletin of the World Health Organization are provided here courtesy of World Health Organization

RESOURCES