Abstract
Salmonella typhimurium LT-2 was compared with radioresistant (B/r) and radiosensitive (Bs−2) strains of Escherichia coli in respect to the survival, deoxyribonucleic acid (DNA) breakdown, and DNA synthesis after X irradiation. It is shown that S. typhimurium LT-2 is about four times more sensitive than E. coli B/r but less sensitive than Bs−2. The DNA breakdown is in S. typhimurium LT-2 lower than the postirradiation breakdown of DNA in both E. coli strains and DNA synthesis proceeds in this bacterium in spite of a much lower survival, as in the radioresistant E. coli B/r.
Full text
PDF





Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Achey P. M., Pollard E. C. Studies on the radiation-induced breakdown of deoxyribonucleic acid in Escherichia coli 15 T L. Radiat Res. 1967 May;31(1):47–62. [PubMed] [Google Scholar]
- BOLLUM F. J. Thermal conversion of nonpriming deoxyribonucleic acid to primer. J Biol Chem. 1959 Oct;234:2733–2734. [PubMed] [Google Scholar]
- BOYCE R. P., HOWARD-FLANDERS P. RELEASE OF ULTRAVIOLET LIGHT-INDUCED THYMINE DIMERS FROM DNA IN E. COLI K-12. Proc Natl Acad Sci U S A. 1964 Feb;51:293–300. doi: 10.1073/pnas.51.2.293. [DOI] [PMC free article] [PubMed] [Google Scholar]
- BURTON K. A study of the conditions and mechanism of the diphenylamine reaction for the colorimetric estimation of deoxyribonucleic acid. Biochem J. 1956 Feb;62(2):315–323. doi: 10.1042/bj0620315. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Billen D., Hewitt R., Jorgensen G. X-ray-induced perturbations in the replication of the bacterial chromosome. Biochim Biophys Acta. 1965 Jul 15;103(3):440–454. doi: 10.1016/0005-2787(65)90137-1. [DOI] [PubMed] [Google Scholar]
- Billen D. Replication of the bacterial chromosome: location of new initiation sites after irradiation. J Bacteriol. 1969 Mar;97(3):1169–1175. doi: 10.1128/jb.97.3.1169-1175.1969. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Dean C. J., Feldschreiber P., Lett J. T. Repair of x-ray damage to the deoxyribonucleic acid in Micrococcus radiodurans. Nature. 1966 Jan 1;209(5018):49–52. doi: 10.1038/209049a0. [DOI] [PubMed] [Google Scholar]
- EMMERSON P. T., HOWARD-FLANDERS P. POST-IRRADIATION DEGRADATION OF DNA FOLLOWING EXPOSURE OF UV-SENSITIVE AND RESISTANT BACTERIA TO X-RAYS. Biochem Biophys Res Commun. 1965 Jan 4;18:24–29. doi: 10.1016/0006-291x(65)90876-4. [DOI] [PubMed] [Google Scholar]
- Frampton E. W., Billen D. X-ray-induced degradation of deoxyribonucleic acid in a polyauxotrophic bacterium. Radiat Res. 1966 May;28(1):109–120. [PubMed] [Google Scholar]
- HILL R. F., SIMSON E. A study of radiosensitive and radioresistant mutants of Escherichia coli strain B. J Gen Microbiol. 1961 Jan;24:1–14. doi: 10.1099/00221287-24-1-1. [DOI] [PubMed] [Google Scholar]
- Hudnik-Plevnik T. A. Effect of x-irradiation on pulse-labelling of ribonucleic acid in Salmonella typhimurium. Biochim Biophys Acta. 1965 Jul 15;103(3):515–516. doi: 10.1016/0005-2787(65)90147-4. [DOI] [PubMed] [Google Scholar]
- MILETIC B., KUCAN Z., ZAJEC L. Synthesis of DNA in x-irradiated Escherichia coli B. Biochem Biophys Res Commun. 1961 Apr 7;4:343–347. doi: 10.1016/0006-291x(61)90215-7. [DOI] [PubMed] [Google Scholar]
- McGrath R. A., Williams R. W. Reconstruction in vivo of irradiated Escherichia coli deoxyribonucleic acid; the rejoining of broken pieces. Nature. 1966 Oct 29;212(5061):534–535. doi: 10.1038/212534a0. [DOI] [PubMed] [Google Scholar]
- McGrath R. A., Williams R. W., Swartzendruber D. C. Breakdown of DNA in x-irradiated Escherichia coli. Biophys J. 1966 Jan;6(1):113–122. doi: 10.1016/S0006-3495(66)86643-2. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Pollard E. C., Achey P. M. The action of ionizing radiation on postirradiation synthesis and degradation of DNA in Escherichia coli 15 T L. Radiat Res. 1966 Mar;27(3):419–433. [PubMed] [Google Scholar]
- STUY J. H. Studies on the radiation inactivation of microorganisms. VI. X-ray induced breakdown of deoxyribonucleic acid in Haemophilus influenzae and in other bacteria. J Bacteriol. 1960 May;79:707–715. doi: 10.1128/jb.79.5.707-715.1960. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Trgovcević Z., Kućan Z. Correlation between the breakdown of deoxyribonucleic acid and radiosensitivity of Escherichia coli. Radiat Res. 1969 Mar;37(3):478–492. [PubMed] [Google Scholar]
