Abstract
In view of the encouraging laboratory findings on the efficacy of intradermal administration of cholera vaccination in small doses, a controlled field trial was undertaken in the Philippines to evaluate the efficacy of the two routes for cholera vaccination. The trial has shown that these routes are effective, both giving a significant degree of protection against cholera. However, the vaccine afforded longer-lasting protection when administered subcutaneously (6 months) than when given intradermally (4 months), and was significantly more effective in children in the 1-5-year age group in this endemic area.
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Selected References
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