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. Author manuscript; available in PMC: 2009 Jun 26.
Published in final edited form as: Neuroscience. 2008 Apr 11;154(3):1143–1153. doi: 10.1016/j.neuroscience.2008.03.082

Table 1.

Effect of kainic acid administration on seizure parameters in young, middle-aged, and aged mice

Mouse strain Age group Dose (mg/kg) Seizure incidence Latency (min.) Duration (min.) Mortality
C57BL/6J Young 15 5/7 55.0±7.7 35.0±15.5 0/7
C57BL/6J Young 20 8/8 55.6±8.1 78.8±9.2 2/8
C57BL/6J Young 25 8/8 59.3±7.3 90.0±14.1 2/8
C57BL/6J Young 30 17/17 38.9±4.8 35.3±7.8 10/17
C57BL/6J Mature 10 1/6 72.0±0.0 55.0±0.0 0/6
C57BL/6J Mature 15 5/7 55.4±15.2 26.4±14.7 0/7
C57BL/6J Mature 20 14/14 41.4±4.9 47.7±7.5 6/14
C57BL/6J Aged 10 5/6 40.0±8.8 61.7±17.9 2/6
C57BL/6J Aged 15 6/6 31.5±3.4 55.2±10.0 2/6
C57BL/6J Aged 20 5/6 19.5±4.3 39.0±24.9 4/6