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Bulletin of the World Health Organization logoLink to Bulletin of the World Health Organization
. 1973;48(6):721–726.

Problems of standardization in clinical chemistry*

J Paul Cali
PMCID: PMC2483069  PMID: 4544783

Abstract

If analytical results in clinical chemistry are to be made meaningful, i.e., accurate, precise, and specific, a systematic approach to their attainment is necessary. Furthermore, because this system is so complex in scope and the need for it is so widespread, it will require international coordination. Agreement on the units of measurement, the production and certification of standard reference materials, and the development of reference methods of demonstrated accuracy will require the support of all segments of clinical chemistry.

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