Abstract
ε34 Is a converting bacteriophage which brings about a glucosylation of the O antigen in the E group salmonella, thus producing antigen 34. Uridine diphosphate glucose is the precursor of antigen 34 and a glucosyl-lipid is an essential intermediate in this process. Mutants of ε34 which cannot produce antigen 34 have been isolated. Cells lysogenic for these mutants are of two types. Type 1 mutant lysogens cannot form the glucosyl-lipid intermediate; those of type 2 can form glucosyl-lipid but are unable to transfer glucose from the lipid to the O antigen.
Full text
PDF
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Baldwin R. L., Barrand P., Fritsch A., Goldthwait D. A., Jacob F. Cohesive sites on the deoxyribonucleic acids from several temperate coliphages. J Mol Biol. 1966 Jun;17(2):343–357. doi: 10.1016/s0022-2836(66)80146-8. [DOI] [PubMed] [Google Scholar]
- HERSHEY A. D. An upper limit to the protein content of the germinal substance of bacteriophage T2. Virology. 1955 May;1(1):108–127. doi: 10.1016/0042-6822(55)90009-x. [DOI] [PubMed] [Google Scholar]
- Hall D. H., Tessman I. T4 mutants unable to induce deoxycytidylate deaminase activity. Virology. 1966 Jun;29(2):339–345. doi: 10.1016/0042-6822(66)90041-9. [DOI] [PubMed] [Google Scholar]
- Lindberg A. A., Holme T. Influence of O side chains on the attachment of the Felix O-1 bacteriophage to Salmonella bacteria. J Bacteriol. 1969 Aug;99(2):513–519. doi: 10.1128/jb.99.2.513-519.1969. [DOI] [PMC free article] [PubMed] [Google Scholar]
- ROBBINS P. W., UCHIDA T. Studies on the chemical basis of the phage conversion of O-antigens in the E-group Salmonellae. Biochemistry. 1962 Mar;1:323–335. doi: 10.1021/bi00908a020. [DOI] [PubMed] [Google Scholar]
- UETAKE H., HAGIWARA S. Genetic cooperation between unrelated phages. Virology. 1961 Apr;13:500–506. doi: 10.1016/0042-6822(61)90281-1. [DOI] [PubMed] [Google Scholar]
- Uchida T., Makino T., Kurahashi K., Uetake H. Biosynthesis of the determinant 34 of the Salmonella O-antigen. Biochem Biophys Res Commun. 1965 Nov 22;21(4):354–360. doi: 10.1016/0006-291x(65)90201-9. [DOI] [PubMed] [Google Scholar]
- Wright A. Mechanism of conversion of the salmonella O antigen by bacteriophageepsilon 34. J Bacteriol. 1971 Mar;105(3):927–936. doi: 10.1128/jb.105.3.927-936.1971. [DOI] [PMC free article] [PubMed] [Google Scholar]