Abstract
In Shandong Province, China, programmes were initiated in 1991 for mass immunization against poliomyelitis and for the immediate reporting of acute flaccid paralysis (AFP). The incidence of non-poliomyelitis AFP was found to be 0.46-0.61 cases per 100,000 children per annum. It appeared that illness resembling the Guillain-Barré syndrome was underreported. The incidence of such illness peaked among children aged 2-3 years. Although laboratory investigations have improved, in 1992 they were still inadequate in nearly a third of confirmed poliomyelitis cases. As the prevalence of wild poliovirus declines in China, reliable laboratory support needs to be established and adequately sensitive and specific AFP surveillance be developed if poliomyelitis is to be eradicated.
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Selected References
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- Andrus J. K., de Quadros C. A., Olive J. M. The surveillance challenge: final stages of eradication of poliomyelitis in the Americas. MMWR CDC Surveill Summ. 1992 Mar;41(1):21–26. [PubMed] [Google Scholar]
- Andrus J. K., de Quadros C., Olivé J. M., Hull H. F. Screening of cases of acute flaccid paralysis for poliomyelitis eradication: ways to improve specificity. Bull World Health Organ. 1992;70(5):591–596. [PMC free article] [PubMed] [Google Scholar]
- Balanant J., Guillot S., Candrea A., Delpeyroux F., Crainic R. The natural genomic variability of poliovirus analyzed by a restriction fragment length polymorphism assay. Virology. 1991 Oct;184(2):645–654. doi: 10.1016/0042-6822(91)90434-d. [DOI] [PubMed] [Google Scholar]
- Biellik R. J., Bueno H., Olive J. M., de Quadros C. Poliomyelitis case confirmation: characteristics for use by national eradication programmes. Bull World Health Organ. 1992;70(1):79–84. [PMC free article] [PubMed] [Google Scholar]
- McKhann G. M., Cornblath D. R., Ho T., Li C. Y., Bai A. Y., Wu H. S., Yei Q. F., Zhang W. C., Zhaori Z., Jiang Z. Clinical and electrophysiological aspects of acute paralytic disease of children and young adults in northern China. Lancet. 1991 Sep 7;338(8767):593–597. doi: 10.1016/0140-6736(91)90606-p. [DOI] [PubMed] [Google Scholar]