Abstract
In a cross-sectional survey of 5420 children in northern Bangladesh, 124 were reported to have night blindness by their parents. Of these, 105 cases along with controls matched for age, sex, and neighbourhood had their scotopic vision examined under standard condition using a luxometer, underwent an ophthalmological examination, and had their serum vitamin A level determined. The mean serum vitamin A level was lowest among children identified as night blind by both their parents and the investigators (16.3 micrograms/dl; 95% confidence interval (CI), 13.9-18.7) and highest among those identified as not night blind by both their parents and the investigators (23.6 micrograms/dl; 95% CI, 21.3-25.9). The results show that parents' report of their children's night blindness had low sensitivity compared with diagnosis using standard observations of scotopic vision with a luxometer.
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Selected References
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- Cohen N., Rahman H., Mitra M., Sprague J., Islam S., Leemhuis de Regt E., Jalil M. A. Impact of massive doses of vitamin A on nutritional blindness in Bangladesh. Am J Clin Nutr. 1987 May;45(5):970–976. doi: 10.1093/ajcn/45.5.970. [DOI] [PubMed] [Google Scholar]
- Cohen N., Rahman H., Sprague J., Jalil M. A., Leemhuis de Regt E., Mitra M. Prevalence and determinants of nutritional blindness in Bangladeshi children. World Health Stat Q. 1985;38(3):317–330. [PubMed] [Google Scholar]
- De Sole G., Belay Y., Zegeye B. Vitamin A deficiency in southern Ethiopia. Am J Clin Nutr. 1987 Apr;45(4):780–784. doi: 10.1093/ajcn/45.4.780. [DOI] [PubMed] [Google Scholar]
- Fawzi W. W., Herrera M. G., Willett W. C., el Amin A., Nestel P., Lipsitz S., Spiegelman D., Mohamed K. A. Vitamin A supplementation and dietary vitamin A in relation to the risk of xerophthalmia. Am J Clin Nutr. 1993 Sep;58(3):385–391. doi: 10.1093/ajcn/58.3.385. [DOI] [PubMed] [Google Scholar]
- Flores H., Campos F., Araujo R. C., Underwood B. A. Assessment of marginal vitamin A deficiency in Brazilian children using the relative dose response procedure. Am J Clin Nutr. 1984 Dec;40(6):1281–1289. doi: 10.1093/ajcn/40.6.1281. [DOI] [PubMed] [Google Scholar]
- Gadomski A. M., Kjolhede C. L., Wittpenn J., Bulux J., Rosas A. R., Forman M. R. Conjunctival impression cytology (CIC) to detect subclinical vitamin A deficiency: comparison of CIC with biochemical assessments. Am J Clin Nutr. 1989 Mar;49(3):495–500. doi: 10.1093/ajcn/49.3.495. [DOI] [PubMed] [Google Scholar]
- Patel P., Gopaldas T., Pant I. A simple field test for identification of night-blindness. Indian J Pediatr. 1989 Mar-Apr;56(2):201–206. doi: 10.1007/BF02726607. [DOI] [PubMed] [Google Scholar]
- Reddy V. Vitamin A deficiency and blindness in Indian children. Indian J Med Res. 1978 Oct;68 (Suppl):26–37. [PubMed] [Google Scholar]
- Rumore M. M. Vitamin A as an immunomodulating agent. Clin Pharm. 1993 Jul;12(7):506–514. [PubMed] [Google Scholar]
- Sommer A., Hussaini G., Muhilal, Tarwotjo I., Susanto D., Saroso J. S. History of nightblindness: a simple tool for xerophthalmia screening. Am J Clin Nutr. 1980 Apr;33(4):887–891. doi: 10.1093/ajcn/33.4.887. [DOI] [PubMed] [Google Scholar]
- Sommer A., Muhilal, Tarwotjo I., Djunaedi E., Glover J. Oral versus intramuscular vitamin A in the treatment of xerophthalmia. Lancet. 1980 Mar 15;1(8168 Pt 1):557–559. doi: 10.1016/s0140-6736(80)91053-3. [DOI] [PubMed] [Google Scholar]
- Sommer A. Nutritional blindness and xerophthalmia. Compr Ther. 1983 Apr;9(4):67–71. [PubMed] [Google Scholar]
- Tielsch J. M., Sommer A. The epidemiology of vitamin A deficiency and xerophthalmia. Annu Rev Nutr. 1984;4:183–205. doi: 10.1146/annurev.nu.04.070184.001151. [DOI] [PubMed] [Google Scholar]
